RebelEM

JUNE 19, 2023

The PATCH-trauma researchers sought to address this critique. PMID: 37314244 Clinical Question: In advanced trauma systems, does prehospital administration of TXA increase the rate of survival with a favorable neurologic outcome in patients at risk for trauma-induced coagulopathy? Prehospital Tranexamic Acid for Severe Trauma.

Blood Transfusions 105

Blood Transfusions Outcomes Administration Hyperthermia / Hypothermia 105

The Skeptics' Guide to EM

JUNE 17, 2023

Her research interests include optimizing pain treatment in children. The National Heart, Lung, and Blood Institute (NHLBI) released an expert panel report in 2014 with evidence-based guidelines for management of sickle cell disease recommending timely administration of parenteral opioids for VOE. [7]

Emergency Department 74

Emergency Department Pediatrics Head Injuries Administration 74

PulmCCM

JANUARY 6, 2025

With financial penalties coming for noncompliance with the new rule, hospital administrators rapidly deployed the alerts to fire on all eligible inpatients. Saudi Arabia is considered an authoritarian society, and internationally significant research projects have important political value to the monarchy. And have they fired.

Sepsis 45

Sepsis Documentation/Coding Hospitals Outcomes 45

RebelEM

FEBRUARY 29, 2024

3, 6 Among patients with stroke or traumatic brain injury (TBI), the risk may be as high as 28%-76% and 23%-60%, respectively. The authors rightfully note future research targets should include how/if the routine use of ceftriaxone increases antibiotic resistance in a population that is already quite vulnerable to devastating infection.

CDC 111

CDC Radiology Radiology Head Injuries 111

EMDocs

NOVEMBER 20, 2023

High certainty of evidence: further research is unlikely to change the confidence in the estimate of the effect. Moderate certainty of evidence: further research is likely to have an important impact and may change the estimate. Low certainty of evidence: further research is very likely to change the estimate.

Resuscitation 99

Resuscitation Fluid Resuscitation Hospitals Research 99

The Skeptics' Guide to EM

SEPTEMBER 28, 2019

Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. Clinical Question: Does the administration of vitamin C to an adult critically ill ICU patient or cardiac surgery patients decrease mortality?

Sepsis 52

Sepsis Shock Outcomes Stroke 52

Downeast Emergency Medicine

APRIL 26, 2021

2][3] If earlier treatment with TXA is better, would there be benefit in its administration in the prehospital setting? Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury. MI or stroke). If so, could this be done safely? JAMA Neurol. 2021;78(3):338–345.

Head Injuries 52

Head Injuries Administration Outcomes Seizures 52

PulmCCM

DECEMBER 11, 2024

But it’s not until the end of the paper, under the heading “Areas of Controversy or Uncertainty and Future Research”, that they finally say why: Sepsis is recognized as a syndrome of acute organ dysfunction due to a dysregulated host response to infection.

Sepsis 45

Sepsis Shock Research Wellness 45

EM Literature of Note

JANUARY 9, 2022

The Annals of Emergency Medicine Podcast continues apace, with free monthly updates from the original research published in the journal: iTunes Link SoundCloud Link Likewise, the Annals of Emergency Medicine Journal Club has published several monthly installments: Predicting Outcomes in Pediatric Pneumonia: Are We Omnipotent or Incompetent?

Hyperthermia / Hypothermia 40

Hyperthermia / Hypothermia Stroke Emergency Department Outcomes 40

ACEP Now

OCTOBER 3, 2023

These guidelines present the best available evidence to support clinical decision making in the prehospital setting when TBI care may have the most significant impact on outcomes; they also establish a research agenda for future investigations. References Lulla A, et al.

Fluid Resuscitation 98

Fluid Resuscitation Documentation/Coding Resuscitation EMS 98

EMDocs

OCTOBER 30, 2023

At the same time, newer research has shown that the diagnostic safety despite withholding contrast in abdominal pain may actually be overstated. However, until more research data is available on this, the results suggest that clinicians should use caution not to overly rely on NCCT to exclude serious intraabdominal pathology.

Radiology 92

Radiology Radiology Emergency Department Hospitals 92

ACEP Now

JULY 6, 2023

Emergency physicians have become leaders in achieving cost efficiency in health care, predominantly through implementation of new processes and research findings, enabling us to achieve significant financial savings. Pediatric Emergency Care Applied Research Network head injury clinical prediction rules are reliable in practice.

Head Injuries 52

Head Injuries Emergency Department Research Pediatrics 52

PulmCCM

JANUARY 4, 2022

For example, should a fluid challenge fail to raise stroke volume [SV], a state of physiological preload intolerance exists and additional volume is arguably harmful ; further attempts to increase tissue perfusion might then be best achieved with vasoactives. For what are intravenous fluids diagnostic?

Wellness 40

Wellness Outcomes Sepsis Stroke 40

Taming the SRU

MAY 3, 2023

However, inhalational administration of epoprostenol requires certain equipment, namely a drug delivery device such as an Aerogen nebulizer (5). Furthermore, these rapid changes in pulmonary vascular resistance can lead to significant reduction in RV stroke volume and subsequent RV dilation & tricuspid regurgitation (16).

Wellness 52

Wellness Hospitals Shock Outcomes 52

RebelEM

FEBRUARY 1, 2024

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 132

Stroke Blood Transfusions Outcomes EMS 132

EB Medicine

MAY 3, 2019

And while safety planning typically is most effective when combined with other interventions, research suggests that it does enhance outpatient treatment engagement after an ED visit and in one study, reduce subsequent suicide attempts by 30% vs usual care. Rockville (MD): Agency for Healthcare Research and Quality (US); 2006. (US

Emergency Department 40

Emergency Department Psychiatric Documentation/Coding Outcomes 40

EB Medicine

AUGUST 1, 2018

Jeff: This DEA designation limits the ability to do research and obtain federal funding for such research. Synthetics were initially developed in the 1980s largely for research purposes. Also, be aware that there are various formulations of cannabis that allow for different routes of administration.

Seizures 40

Seizures Hyperthermia / Hypothermia Administration Dehydration 40

Mind The Bleep

DECEMBER 6, 2023

For example: in a study on stroke, if the mean age of participants in the treatment arm is 25 years, compared to 75 years in the placebo arm, are the results going to be valid? Do the measured outcomes actually answer the research question? Was the administration difficult? Did participants drop-out? If yes, why?

Outcomes 52

Outcomes Evidence-Based Practice Research Stroke 52

Pediatric Emergency Playbook

JANUARY 1, 2017

CRIES is a 10-point scale, using a physiologic basis similar to APGAR: Crying; Requires increased oxygen administration (distress and breath-holding); Increased vital signs; Expression; and Sleeplessness ( Krechel 1995 ). Once the pain is controlled, less frequent administration of medications, with frequent reassessments, are indicated.

Pediatrics 40

Pediatrics Soft Tissue Injuries Burns Emergency Department 40

EMDocs

NOVEMBER 4, 2024

80 It can be caused by traumatic nerve, spinal cord, or brain injury (including stroke) or can be a sequela of conditions like diabetes, HIV/AIDS, postherpetic neuropathies, multiple sclerosis, cancer, or chemotherapies. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Emerg Med J. J Emerg Med.

Emergency Department 105

Emergency Department Fractures Burns EMS 105

ACEP Now

DECEMBER 11, 2023

Food and Drug Administration regarding the efficacy of oral phenylephrine as a nasal decongestant, caused a ruckus. 1 This publication would not come as a surprise to those following the past 15 years of efforts by the research teams examining phenylephrine. Food and Drug Administration. References U.S.

Administration 64

Administration Outcomes Research Stroke 64

Dr. Smith's ECG Blog

APRIL 8, 2015

Administrative data from an integrated health system of 11 Southern California EDs were used to identify cardiac outcomes after ED presentation for syncope from January 1, 2002, to December 31, 2005. to 1.45) for fatal or nonfatal stroke. g/dL —Hypotension (obviously!) to 2.73), 2.66 (95 percent confidence interval, 1.69 to 3.80).

Emergency Department 52

Emergency Department EKG/ECG Outcomes Seizures 52

Don't Forget the Bubbles

NOVEMBER 18, 2024

Various studies, such as those pooling data from the National Neonatal Research Database, indicate that the incidence of hypotension varies based on neonatal age, with the highest rates observed immediately post-birth and within the first days of life. CO = SV x HR SV is Stroke Volume (the amount of blood ejected with each heartbeat).

Sepsis 59

Sepsis Shock Hyperthermia / Hypothermia Administration 59

PEMBlog

MAY 9, 2024

So the risk of febrile seizures is increased after administration of diphtheria, tetanus, toxoid, and whole cell pertussis, along with measles, mumps, rubella, and MMR with varicella vaccines. More research is needed. In kids up to two and a half years of age, breastfeeding may be a preventative factor for febrile seizures.

Seizures 59

Seizures Pediatrics Wellness Emergency Department 59

ACEP Now

DECEMBER 7, 2024

The use of thrombolytics for acute ischemic stroke may be one of the most controversial topics in emergency medicine during the last several decades. 1 The reason is understandablethrombolytics in stroke is a high-risk, higher-reward treatment. This debate recurs in multiple forums including many previous pieces in ACEP Now.

Stroke 98

Stroke Research Hospitals Outcomes 98