Don't Forget the Bubbles

MAY 17, 2023

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Original clinical studies The impact of the early onset neonatal sepsis calculator on antibiotic initiation: a single center study in Israel. Tritos NA, et al.

Pediatrics 72

Pediatrics X-Ray Interpretation Sepsis Fractures 72

EMDocs

JULY 1, 2023

Upon further research in the 1970’s, retrospective data from autopsies of those patients showed coronary aneurysms 5 Pathophysiology: Kawasaki Disease is a vasculitis of medium sized arteries. This is the only situation in which aspirin is recommended for administration in children, as the benefits outweigh the risks of Reye syndrome.

EMS 91

EMS Infectious Diseases Pediatrics Research 91

Don't Forget the Bubbles

NOVEMBER 15, 2023

Currently, the administration of water for the paediatric population is based on the Holliday-Segar formula (100ml/kg/day for the first 10kg of weight, 50ml/kg/day for the second 10kg of weight and 20ml/kg/day for weight over 20kg). Jasmine, a hypothetical case Jasmine is a 5-year-old girl weighing 18kg admitted to PICU with suspected sepsis.

Resuscitation 80

Resuscitation Dehydration Administration Shock 80

PulmCCM

JANUARY 4, 2022

As well, the volume of administration might be much lower than 500 mL, with previous research indicating that 4 mL/kg of crystalloid was an optimal volume needed to increase mean systemic filling pressure. Yet, studies of fluid challenges have actually investigated greater rates of infusion including 50 mL in 10 seconds !

Wellness 40

Wellness Outcomes Sepsis Stroke 40

Dr. Smith's ECG Blog

MAY 19, 2020

pulmonary embolism, sepsis, etc.), The gold standard technique for diagnosing coronary spasm is administration of high-dose intracoronary acetylcholine boluses with the response evaluated by invasive contrast angiography. The diagnosis of MINOCA should exclude: 1) other overt causes for elevated troponin (e.g., myocarditis).

CPR 52

CPR EKG/ECG Shock Ultrasounds 52

RebelEM

NOVEMBER 30, 2023

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. What They Did: Researchers performed a systematic review and meta-analysis.

Sepsis 121

Sepsis Fluid Resuscitation Resuscitation Administration 121

RebelEM

AUGUST 14, 2023

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

Sepsis 98

Sepsis Outcomes Administration EMS 98

EMDocs

DECEMBER 18, 2023

Introduction Sepsis and septic shock are life-threatening conditions characterized by severe systemic inflammation and organ dysfunction due to a dysregulated host response to infection. 3,4 Prompt recognition and management of sepsis and septic shock are paramount for the ED clinician. vs. 0.91), positive predictive value (0.27

Sepsis 90

Sepsis Fluid Resuscitation Resuscitation Shock 90

RebelEM

MAY 29, 2023

Background: Sepsis can induce numerous physiologic derangements. Judicious fluid resuscitation is indicated in patients with signs of hypo perfusion but is often inadequate necessitating the administration of vasoactive medications. septic shock). Through these mechanisms it restores vasoregulation. 95% CI 15.4 95% CI 15.4

Shock 145

Shock Fluid Resuscitation Sepsis Resuscitation 145

Don't Forget the Bubbles

MARCH 31, 2025

The Bridge is a Postgraduate Doctor in Training (PGDiT)- led paediatric research forum in Yorkshire and Humber, UK, with the aim of bridging the gap in research access among PGDiT. Association between fluid overload and mortality in children with sepsis: a systematic review and meta-analysis. BMJ Paediatr Open. Whats it about?

Sepsis 59

Sepsis Fluid Resuscitation Shock Resuscitation 59

ACEP Now

MARCH 6, 2024

Every year, the volume of published research continues to outpace capacity to consume. The simplicity of tenecteplase administration makes its use likely the preferred agent for treating acute ischemic stroke. The post Fourteen Emergency Medicine Research Gems from 2023 appeared first on ACEP Now. Gotta catch ‘em all!”

Research 52

Research Airway Management Stroke Outcomes 52

RebelEM

MAY 15, 2024

Early administration of antibiotics is the only factor known to reduce this mortality. Antibiotics are effectively the only thing standing between these patients and overwhelming sepsis. Early administration of antibiotics is the only factor known to reduce this mortality. BMC Health Services Research. Epub 2017 Nov 22.

Infectious Diseases 98

Infectious Diseases Administration Sepsis Anaphylaxis 98

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

Sepsis 52

Sepsis Shock Hospitals Infectious Diseases 52

EB Medicine

OCTOBER 1, 2018

This month, we’ll be talking Updates and Controversies in the Early Management of Sepsis and Septic Shock. We have a special episode for you this month… We’ve brought Dr. Jeremy Rose, one of the peer reviewers, and a sepsis expert, on with us to talk through the content this month. Jeff : Sepsis chair. Sepsis-3!!

Sepsis 40

Sepsis Shock Fluid Resuscitation Hospitals 40

RebelEM

OCTOBER 5, 2023

Background: Community-acquired pneumonia (CAP) can lead to pulmonary and systemic inflammation, resulting in impaired gas exchange, sepsis, organ failure, and an increased risk of death. Strengths: The investigators framed a research question centered on patient outcomes, ensuring the study’s relevance and practicality.

Research 94

Research Outcomes Administration Shock 94

The Skeptics' Guide to EM

SEPTEMBER 28, 2019

Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. But you remember seeing in the news there was a study claiming vitamin C could cure sepsis. You wonder if giving vitamin C will affect her outcome?

Sepsis 52

Sepsis Shock Outcomes Stroke 52

Northwestern EM Blog

JANUARY 24, 2022

Acidosis Acidosis in shock states can present from multiple different sources, including sepsis, hypoxemia, ingestions, hyperlactatemia from hypoperfusion, amongst others. At those levels, bicarbonate administration has not been shown to improve cardiac output, MAP or pressor response. Critical Care Research and Practice.

Anaphylaxis 52

Anaphylaxis Shock Sepsis Resuscitation 52

PulmCCM

DECEMBER 10, 2023

Answering this research question has been made more difficult by pip-tazo’s possible status as a pseudo-nephrotoxin (elevating creatinine levels in the blood without harming the kidneys) and frequent co-administration with vancomycin, a known nephrotoxin.

Seizures 52

Seizures Sepsis Academics Administration 52

The Skeptics' Guide to EM

DECEMBER 11, 2021

Date: December 10th, 2021 Guest Skeptic: Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. Back in 2019 we were talking about Vitamin C for sepsis ( SGEM#268 ). Not much has changed over the last two years.

Sepsis 40

Sepsis Shock Outcomes Academics 40

Don't Forget the Bubbles

JUNE 10, 2024

NEC remains a significant challenge in neonatology, prompting ongoing research and clinical trials to understand its pathogenesis better, improve prevention strategies, and develop more effective treatments. Differential diagnoses include septic ileus, and infection causes such as sepsis, meningitis and pneumonia. Hunter, C.J.,

Pediatrics 40

Pediatrics Sepsis Fluid Resuscitation Outcomes 40

Thinking Critical Care

MAY 18, 2023

In 1983 I was an Englishman abroad, the London anaesthetist who was appointed to be the English anaesthetist on the Shock Team only because the outstanding candidate from Oxford had preferred to take up a job doing muscle relaxant research with Kitz and Katz in the USA. 4] The research agenda at the time was broad.

Shock 40

Shock Research Sepsis Resuscitation 40

EM Updates

JUNE 15, 2021

Administrative logistics demanded that patients receiving ongoing care in the emergency department be formally admitted to the hospital; we were therefore enjoined to admit these patients to ourselves and therefore formed the Emergency Department Admitting Team. The study was approved by the MMC institutional review board. N Engl J Med.

Emergency Department 52

Emergency Department Hospitals Outcomes Wellness 52

PulmCCM

JANUARY 31, 2025

There’s no diagnostic test for sepsis, which leads to high rates of overdiagnosis, delayed care from missed cases, and flawed clinical research. Various new “sepsis tests” claim to solve the problem of diagnostic imprecision in the early management of suspected sepsis. are reported in the preprint.

Sepsis 59

Sepsis Emergency Department Research Administration 59

Don't Forget the Bubbles

NOVEMBER 18, 2024

Various studies, such as those pooling data from the National Neonatal Research Database, indicate that the incidence of hypotension varies based on neonatal age, with the highest rates observed immediately post-birth and within the first days of life. Hypotension in the setting of sepsis may be one of the first signs of a systemic infection.

Sepsis 59

Sepsis Shock Hyperthermia / Hypothermia Administration 59

EMDocs

JANUARY 20, 2025

Sepsis There has been much controversy over the last two decades around the various nuances of volume resuscitation in ED patients with suspected sepsis, much of which goes beyond the scope of this limited review. It may be reasonable to consider IV fluid administration in patients with moderate dehydration or prolonged vomiting.

Dehydration 75

Dehydration Fluid Resuscitation Sepsis Resuscitation 75

PulmCCM

MARCH 11, 2024

Ascension and UPenn test automatic palliative care consults Palliative care programs are sometimes pitched to administrators on the basis of their potential to reduce costs, by shortening length-of-stay or intensity of expensive and unhelpful therapies at the end of life. This is not a hot research area.)

Hospice 52

Hospice Documentation/Coding Administration Hospitals 52

Don't Forget the Bubbles

JANUARY 1, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. 2023 Dec 12 Pediatric Sepsis Diagnosis, Management, and Sub-phenotypes. The first one highlights the impact of the recent pandemic on children. Pawlowski TW, et al.

Pediatrics 98

Pediatrics Ultrasounds Blood Transfusions Sepsis 98

EMDocs

FEBRUARY 8, 2025

WHO fungal priority pathogens list to guide research, development and public health action. Core recommendations for Antifungal stewardship: A statement of the Mycoses Study Group Education and Research Consortium. Routine versus selective antifungal administration for control of fungal infections in patients with cancer.

Infectious Diseases 71

Infectious Diseases EMS COPD Research 71

Don't Forget the Bubbles

DECEMBER 9, 2024

Clinical recommendations for pain, sedation, withdrawal, and delirium assessment in critically ill infants and children Pediatric Acute Lung Injury and Sepsis Investigators ( PALISI ). Duration of drug administration in days e.g. 8 days of midazolam infusion. 4-hourly assessments using a withdrawal observation chart. 2023;207(1):17-28.

Pediatrics 59

Pediatrics Sepsis Hospitals Administration 59

PulmCCM

OCTOBER 23, 2023

Answering this research question has been made more difficult by pip-tazo’s possible status as a pseudo-nephrotoxin (elevating creatinine levels in the blood without harming the kidneys) and frequent co-administration with vancomycin, a known nephrotoxin.

Hospitals 98

Hospitals COPD Emergency Department CDC 98