RebelEM

MAY 29, 2023

Judicious fluid resuscitation is indicated in patients with signs of hypo perfusion but is often inadequate necessitating the administration of vasoactive medications. Most of the research on the use of MB has been in patients with vasoplegia following cardiopulmonary bypass. septic shock). 95% CI 15.4 95% CI 15.4 95% CI 15.4

Shock 145

Shock Fluid Resuscitation Sepsis Resuscitation 145

Sensible Medicine

AUGUST 21, 2023

On yesterday’s podcast , I talked with Bobby Yeh, an academic cardiologist who made a compelling case for enhancing credibility of observational research. The reasons are multiple, but I will articulate a few: Most epidemiological studies are done from large data sets that are not collected for the purpose of research.

Administration 98

Administration Outcomes Research COPD 98

RebelEM

JUNE 19, 2023

The PATCH-trauma researchers sought to address this critique. PMID: 37314244 Clinical Question: In advanced trauma systems, does prehospital administration of TXA increase the rate of survival with a favorable neurologic outcome in patients at risk for trauma-induced coagulopathy? Prehospital Tranexamic Acid for Severe Trauma.

Blood Transfusions 105

Blood Transfusions Outcomes Administration Hyperthermia / Hypothermia 105

The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. However, the efficacy of naloxone in improving outcomes in such cardiac arrests remains a topic of ongoing research and debate. Clinical Question: Is naloxone administration in undifferentiated OHCA associated with survival to hospital discharge?

Hospitals 103

Hospitals CPR EMS Outcomes 103

Sensible Medicine

NOVEMBER 30, 2023

Typically, we place the burden on manufacturers to show that their products improve health outcomes prior to sale. Why can’t GRAIL—with its multibillion dollar evaluation—pay for their own research? We don’t know all the side effects and harms of GRAIL, and downstream interventions.

Research 145

Research Radiology Radiology Administration 145

The Trauma Pro

SEPTEMBER 20, 2023

Researchers from the US Army performed a retrospective registry study on a sample of military casualties over four years. The primary outcome was mortality, and secondary outcomes included the need for surgery, fluid and blood infusions, and the use of a massive transfusion protocol.

Military 113

Military Blood Transfusions Administration Outcomes 113

Don't Forget the Bubbles

DECEMBER 25, 2023

Interpreting Research Outcomes with a Little Bathroom Humour You have learned a method for how to read a research paper , and now you are faced with a bunch of outcomes. There are primary, secondary, composite , and safety outcomes. What are these outcomes? What should you focus on?

Research 83

Research Outcomes Fractures Pediatrics 83

RebelEM

JULY 3, 2023

What They Did: Researchers conducted a multicenter, retrospective cohort study in three community hospitals and two freestanding emergency departments. Secondary outcome All secondary outcomes were found to be similar (Not statistically significant) between groups (See table above). received CaCl 89.3%

Administration 91

Administration Outcomes Documentation/Coding Emergency Department 91

RebelEM

SEPTEMBER 7, 2023

More research is needed to inform preventive treatment strategies for seizures in patients with spontaneous intracerebral hemorrhage (ICH). OUTCOMES Primary: Occurrence of at least one clinical or electrographic seizure recorded on continuous EEG within 72 hours after inclusion. The primary outcome was patient-oriented.

Seizures 123

Seizures Stroke Outcomes Research 123

ACEP Now

MARCH 6, 2024

Every year, the volume of published research continues to outpace capacity to consume. 4 Repeated trials have not shown alteplase to have any signal of better outcomes, nor tenecteplase to have an association with increased adverse events. Gotta catch ‘em all!” How Best to Stop the Bleeding in Trauma? percent to 38.3

Research 52

Research Airway Management Stroke Outcomes 52

The Skeptics' Guide to EM

OCTOBER 19, 2024

Ketamine’s administration is flexible, with several routes available including IV, intranasal (IN), and more recently, nebulized forms. Each method has its advantages, and ongoing research continues to refine the efficacy and safety of these delivery methods in acute pain management in the ED​​. mg/kg, 1 mg/kg, and 1.5

Emergency Department 94

Emergency Department EMS Research Administration 94

Taming the SRU

MAY 11, 2024

r1 clinical knowledge - r4 capstone - research grand rounds - the art of em - Community corner - PEM Lecture r1 Clinical knowledge: transplant complications WITH dr. gabor Time-sensitive peri-transplant emergencies: Bleeding fistula- stop the bleed. Flood syndrome- start fluids, give antibiotics, consult surgery. Ways to get involved?

Administration 92

Administration Resuscitation Fluid Resuscitation Research 92

RebelEM

OCTOBER 5, 2023

Secondary Outcome By day 90, mortality was 9.3% Strengths: The investigators framed a research question centered on patient outcomes, ensuring the study’s relevance and practicality. Control: Normal Saline via continuous infusion according to the same regimen used in the hydrocortisone group. to −0.8).

Research 94

Research Outcomes Administration Shock 94

RebelEM

AUGUST 14, 2023

4 XBJ received approval from the China Food and Drug Administration in 2004, 2 although the FDA of the United States has not approved it. Secondary Outcome Results: ICU mortality: placebo 20.0% Investigators asked a patient-centered research question. The primary outcome was patient oriented. vs. XBJ 14.4%

Sepsis 97

Sepsis Outcomes Administration EMS 97

PulmCCM

JANUARY 6, 2025

With financial penalties coming for noncompliance with the new rule, hospital administrators rapidly deployed the alerts to fire on all eligible inpatients. A cluster randomized trial using all-cause mortality as an outcome was always needed to determine whether EMR alerts improve outcomes for suspected severe infection.

Sepsis 45

Sepsis Documentation/Coding Hospitals Outcomes 45

ACEP Now

SEPTEMBER 6, 2024

This is not unwelcome in the slightest, as tenecteplase administration in stroke is more straightforward than the bolus-plus-infusion requirement for alteplase. 4 Overall, good or excellent outcomes were seen in 79 percent of the reteplase cohort versus 70 percent of those receiving alteplase.

Research 49

Research Stroke Outcomes Sepsis 49

EMDocs

JUNE 8, 2023

and 9 hours after onset of symptoms, with non-infarcted brain tissue, does the administration of alteplase improve functional outcome at 90 days? and 9 hours of symptom onset; stroke symptoms that started during sleep were assumed to have started halfway between the actual last known well and the time of wake-up. to 53.54, p=0.053).

Stroke 95

Stroke Administration Documentation/Coding Outcomes 95

Mind The Bleep

JANUARY 18, 2024

Introduction Starting my research journey as a medical student has been an incredible and transformative experience. In this article, I wholeheartedly share my personal journey, and the invaluable lessons I’ve learned along the way, and offer friendly tips to fellow medical students who aspire to delve into the world of research.

Research 52

Research Administration Hospitals Outcomes 52

University of Maryland CC Project

JANUARY 31, 2024

Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan. Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan.

Administration 40

Administration Sepsis Research Outcomes 40

Sensible Medicine

NOVEMBER 14, 2023

Stefan Kertesz is Professor of Medicine at the Heersink School of Medicine at the University of Alabama at Birmingham where his work includes leading VA and non-VA supported research focused on homeless healthcare and issues related to pain and opioids. These higher quality studies usually achieved better outcomes.

Research 134

Research Psychiatric CDC Best Practices 134

The Skeptics' Guide to EM

JUNE 17, 2023

Her research interests include optimizing pain treatment in children. The National Heart, Lung, and Blood Institute (NHLBI) released an expert panel report in 2014 with evidence-based guidelines for management of sickle cell disease recommending timely administration of parenteral opioids for VOE. [7]

Emergency Department 74

Emergency Department Pediatrics Head Injuries Administration 74

Don't Forget the Bubbles

NOVEMBER 29, 2023

Intensive Care Research , 1 (3-4), pp.60-64. Even though sedation after endotracheal intubation (ETI) reduces the risk of self-extubation, uncontrolled pain, and awakening awareness, several small single-centre studies demonstrate low rates of sedative drug administration after ETI in the emergency department (ED). DOI: 10.1097/ANA.0000000000000275

Airway Management 135

Airway Management Emergency Department Resuscitation Psychiatric 135

RebelEM

FEBRUARY 29, 2024

1, 2 Its occurrence often portends worse outcomes in intubated patients, whose projected hospital course was already tenuous. SECONDARY OUTCOMES At day 28 , ceftriaxone group had (vs placebo): Lower VAP risk (20% vs 36%); hazard ratio 0.62 4, 8 Paper: Dahyot-Fizelier, C.,

CDC 111

CDC Radiology Radiology Head Injuries 111

ACEP Now

JULY 7, 2023

Since 2020 to 2021, the Drug Enforcement Administration has reported a sharp rise in xylazine use across the U.S., Prior to medical school, she received her MBA in Healthcare Management and currently works on health policy and outcomes-based research. US Department of Justice, Drug Enforcement Administration.

Forensics 98

Forensics Airway Management Emergency Department Administration 98

Sensible Medicine

NOVEMBER 28, 2023

People can rise through the academic ranks as gifted clinicians, creative and effective educators, and talented administrators. [i] i] Though I’ve never been a traditional researcher, I’ve added quite a bit to “medical literature” over the years. Being perfectly honest, not all the articles have aged well.

Stroke 98

Stroke Academics Outcomes Administration 98

Emergency Medicine Journal

AUGUST 21, 2024

1 The CFS has become widely adopted in research and clinical settings and has been recommended in the UK for routine administration with adults aged 65+ years with unscheduled hospital attendances. The Clinical Frailty Scale (CFS) uses clinician judgement to quantify the functional impacts of multidimensional health deficits.

Geriatric Emergencies 52

Geriatric Emergencies Administration Research Outcomes 52

Emergency Medicine Journal

NOVEMBER 28, 2023

Meaningful measurement for older people living with frailty would include additional person-centred outcomes of healthcare knowledge, shared decision-making, and situational security. The eight-item PROM-OPAC considers outcome goals specific to this population and was observed here to have metric reliability and validity.

Outcomes 40

Outcomes Administration Hospitals Research 40

Cook County EM Blog

APRIL 27, 2022

2019.09.007 What : Retrospective cohort study of all droperidol administrations between January 2012 and April 2018 at an academic and pediatric emergency department in the US with 77,000 annual visits. Zero deaths were attributed to droperidol administration. Zero deaths were attributed to droperidol administration.

Administration 52

Administration EKG/ECG Emergency Department EMS 52

EMDocs

NOVEMBER 20, 2023

High certainty of evidence: further research is unlikely to change the confidence in the estimate of the effect. Moderate certainty of evidence: further research is likely to have an important impact and may change the estimate. Low certainty of evidence: further research is very likely to change the estimate.

Resuscitation 99

Resuscitation Fluid Resuscitation Hospitals Research 99

Don't Forget the Bubbles

OCTOBER 2, 2024

Moderate-quality evidence is available for bolus administration of hypertonic saline, while only low-quality evidence supports continuous administration. No studies involving mannitol administration met the foundation’s inclusion criteria. The study additionally only measures ICP one hour after bolus administration.

Administration 49

Administration Pediatrics Outcomes Research 49

ACEP Now

SEPTEMBER 3, 2024

These stakeholders are similarly shielded in court when adverse patient outcomes, such as negligent deaths, occur under their management or when the bought-out companies are challenged for anticompetitive business practices overseen by the PE firm. Center for Economic and Policy Research (CEPR). Finance research letters, forthcoming.

Hospitals 113

Hospitals Radiology Radiology Emergency Department 113

EMDocs

JANUARY 29, 2024

hypertensive emergency, need for thrombolytic administration) [1]. Finally, anticipating and addressing known complications such as seizures, increased intracranial pressure, or cerebral edema with appropriate measures, including antiepileptic drugs or osmotic agents, is essential for improving patient outcomes. Stroke 2019; 50:e344.

Stroke 91

Stroke Outcomes EMS Seizures 91

Ziqitza HealthCare Ltd

JUNE 18, 2023

Ziqitza Healthcare ltd embraces precision medicine by leveraging AI to analyze genomic data, enabling the delivery of tailored therapies to patients for improved treatment outcomes. Ziqitza Limited incorporates AI-powered systems to streamline administrative tasks, allowing their staff to focus more on direct patient care.

Documentation/Coding 52

Documentation/Coding Administration Ambulance Services Outcomes 52

American Medical Compliance

APRIL 23, 2024

Our Continuing Medical Education (CME) program is committed to enhancing the knowledge, skills, and professional performance of healthcare providers to improve healthcare outcomes. Furthermore, a population-based echocardiographic research in Northern China reported a prevalence of 3.5%

Research 52

Research Administration Outcomes 52

ACEP Now

OCTOBER 3, 2023

These guidelines present the best available evidence to support clinical decision making in the prehospital setting when TBI care may have the most significant impact on outcomes; they also establish a research agenda for future investigations. There are at least 600 TBI-related hospitalizations and 175 TBI-related deaths per day.

Fluid Resuscitation 98

Fluid Resuscitation Documentation/Coding Resuscitation EMS 98

The Skeptics' Guide to EM

MARCH 18, 2023

Association of early oseltamivir with improved outcomes in hospitalized children with influenza, 2007-2020. Association of early oseltamivir with improved outcomes in hospitalized children with influenza, 2007-2020. She is also the President of the Junior Section of the Society for Pediatric Research. JAMA Pediatr. JAMA Pediatr.

Pediatrics 40

Pediatrics Infectious Diseases Administration Outcomes 40

The Skeptics' Guide to EM

SEPTEMBER 28, 2019

The Effect of Vitamin C on Clinical Outcome in Critically Ill Patients: A Systematic Review with Meta-Analysis of Randomized Controlled Trials. The Effect of Vitamin C on Clinical Outcome in Critically Ill Patients: A Systematic Review with Meta-Analysis of Randomized Controlled Trials. Critical Care Medicine. Critical Care Medicine.

Sepsis 52

Sepsis Shock Outcomes Stroke 52