ACEP Now

MARCH 11, 2025

1 Further, a Cochrane review found that LMWH is associated with improved outcomes compared with UFH including reduced incidence of major hemorrhage (odds ratio [OR]=0.69; 95 percent CI, 0.50-0.95) First, UFH is often perceived as stronger than alternatives, partially owing to the intravenous route of administration. Ann Emerg Med.

Hospitals 52

Hospitals Administration Outcomes Stroke 52

The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. However, the efficacy of naloxone in improving outcomes in such cardiac arrests remains a topic of ongoing research and debate. Clinical Question: Is naloxone administration in undifferentiated OHCA associated with survival to hospital discharge?

Hospitals 104

Hospitals CPR EMS Outcomes 104

RebelEM

JULY 3, 2023

What They Did: Researchers conducted a multicenter, retrospective cohort study in three community hospitals and two freestanding emergency departments. Secondary outcome All secondary outcomes were found to be similar (Not statistically significant) between groups (See table above). received CaCl 89.3%

Administration 96

Administration Outcomes Documentation/Coding Emergency Department 96

RebelEM

SEPTEMBER 7, 2023

More research is needed to inform preventive treatment strategies for seizures in patients with spontaneous intracerebral hemorrhage (ICH). OUTCOMES Primary: Occurrence of at least one clinical or electrographic seizure recorded on continuous EEG within 72 hours after inclusion. The primary outcome was patient-oriented.

Seizures 130

Seizures Stroke Outcomes Research 130

The Skeptics' Guide to EM

OCTOBER 19, 2024

Ketamine’s administration is flexible, with several routes available including IV, intranasal (IN), and more recently, nebulized forms. Each method has its advantages, and ongoing research continues to refine the efficacy and safety of these delivery methods in acute pain management in the ED​​. mg/kg, 1 mg/kg, and 1.5

Emergency Department 100

Emergency Department EMS Research Administration 100

Sensible Medicine

NOVEMBER 30, 2023

Typically, we place the burden on manufacturers to show that their products improve health outcomes prior to sale. Why can’t GRAIL—with its multibillion dollar evaluation—pay for their own research? We don’t know all the side effects and harms of GRAIL, and downstream interventions.

Research 145

Research Radiology Radiology Administration 145

The Trauma Pro

SEPTEMBER 20, 2023

Researchers from the US Army performed a retrospective registry study on a sample of military casualties over four years. The primary outcome was mortality, and secondary outcomes included the need for surgery, fluid and blood infusions, and the use of a massive transfusion protocol.

Military 113

Military Blood Transfusions Administration Outcomes 113

Don't Forget the Bubbles

DECEMBER 25, 2023

Interpreting Research Outcomes with a Little Bathroom Humour You have learned a method for how to read a research paper , and now you are faced with a bunch of outcomes. There are primary, secondary, composite , and safety outcomes. What are these outcomes? What should you focus on?

Research 83

Research Outcomes Fractures Pediatrics 83

PulmCCM

JANUARY 6, 2025

With financial penalties coming for noncompliance with the new rule, hospital administrators rapidly deployed the alerts to fire on all eligible inpatients. A cluster randomized trial using all-cause mortality as an outcome was always needed to determine whether EMR alerts improve outcomes for suspected severe infection.

Sepsis 45

Sepsis Documentation/Coding Hospitals Outcomes 45

ACEP Now

SEPTEMBER 6, 2024

This is not unwelcome in the slightest, as tenecteplase administration in stroke is more straightforward than the bolus-plus-infusion requirement for alteplase. 4 Overall, good or excellent outcomes were seen in 79 percent of the reteplase cohort versus 70 percent of those receiving alteplase.

Research 49

Research Stroke Outcomes Sepsis 49

Mind The Bleep

JANUARY 18, 2024

Introduction Starting my research journey as a medical student has been an incredible and transformative experience. In this article, I wholeheartedly share my personal journey, and the invaluable lessons I’ve learned along the way, and offer friendly tips to fellow medical students who aspire to delve into the world of research.

Research 52

Research Administration Hospitals Outcomes 52

University of Maryland CC Project

JANUARY 31, 2024

Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan. Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan.

Administration 40

Administration Sepsis Research Outcomes 40

Mind The Bleep

APRIL 10, 2025

Examples of LLMs used in healthcare are: The main aims of using AI in healthcare would be to reduce costs, improve patient outcomes and medical education. AI can book appointments and perform other administrative tasks, for instance, retrieving medical information and billing. National Bureau of Economic Research Roberta Kwok (2023).

Documentation/Coding 52

Documentation/Coding Research Outcomes Administration 52

The Skeptics' Guide to EM

JUNE 17, 2023

Her research interests include optimizing pain treatment in children. The National Heart, Lung, and Blood Institute (NHLBI) released an expert panel report in 2014 with evidence-based guidelines for management of sickle cell disease recommending timely administration of parenteral opioids for VOE. [7]

Emergency Department 74

Emergency Department Pediatrics Head Injuries Administration 74

Sensible Medicine

NOVEMBER 28, 2023

People can rise through the academic ranks as gifted clinicians, creative and effective educators, and talented administrators. [i] i] Though I’ve never been a traditional researcher, I’ve added quite a bit to “medical literature” over the years. Being perfectly honest, not all the articles have aged well.

Stroke 99

Stroke Academics Outcomes Administration 99

Emergency Medicine Journal

AUGUST 21, 2024

1 The CFS has become widely adopted in research and clinical settings and has been recommended in the UK for routine administration with adults aged 65+ years with unscheduled hospital attendances. The Clinical Frailty Scale (CFS) uses clinician judgement to quantify the functional impacts of multidimensional health deficits.

Geriatric Emergencies 52

Geriatric Emergencies Administration Research Outcomes 52

Emergency Medicine Journal

NOVEMBER 28, 2023

Meaningful measurement for older people living with frailty would include additional person-centred outcomes of healthcare knowledge, shared decision-making, and situational security. The eight-item PROM-OPAC considers outcome goals specific to this population and was observed here to have metric reliability and validity.

Outcomes 40

Outcomes Administration Research Hospitals 40

EMDocs

NOVEMBER 20, 2023

High certainty of evidence: further research is unlikely to change the confidence in the estimate of the effect. Moderate certainty of evidence: further research is likely to have an important impact and may change the estimate. Low certainty of evidence: further research is very likely to change the estimate.

Resuscitation 103

Resuscitation Fluid Resuscitation Hospitals Research 103

Don't Forget the Bubbles

OCTOBER 2, 2024

Moderate-quality evidence is available for bolus administration of hypertonic saline, while only low-quality evidence supports continuous administration. No studies involving mannitol administration met the foundation’s inclusion criteria. The study additionally only measures ICP one hour after bolus administration.

Administration 49

Administration Pediatrics Outcomes Research 49

EMDocs

JANUARY 29, 2024

hypertensive emergency, need for thrombolytic administration) [1]. Finally, anticipating and addressing known complications such as seizures, increased intracranial pressure, or cerebral edema with appropriate measures, including antiepileptic drugs or osmotic agents, is essential for improving patient outcomes. Stroke 2019; 50:e344.

Stroke 98

Stroke Outcomes EMS Seizures 98

Ziqitza HealthCare Ltd

JUNE 18, 2023

Ziqitza Healthcare ltd embraces precision medicine by leveraging AI to analyze genomic data, enabling the delivery of tailored therapies to patients for improved treatment outcomes. Ziqitza Limited incorporates AI-powered systems to streamline administrative tasks, allowing their staff to focus more on direct patient care.

Documentation/Coding 52

Documentation/Coding Administration Ambulance Services Outcomes 52

American Medical Compliance

APRIL 23, 2024

Our Continuing Medical Education (CME) program is committed to enhancing the knowledge, skills, and professional performance of healthcare providers to improve healthcare outcomes. Furthermore, a population-based echocardiographic research in Northern China reported a prevalence of 3.5%

Research 52

Research Administration Outcomes 52

The Skeptics' Guide to EM

AUGUST 24, 2024

Interests include information systems and digital health, research and education. This procedure involves the administration of a local anesthetic into the plane between the serratus anterior muscle and the rib cage, targeting the thoracic intercostal nerves that supply sensation to the chest wall.

Fractures 54

Fractures Emergency Department Ultrasounds Radiology 54

The Skeptics' Guide to EM

FEBRUARY 27, 2021

Rapid Administration of Methoxyflurane to Patients in the Emergency Department (RAMPED): A Randomised controlled trial of Methoxyflurane vs Standard care. […] The post SGEM#320: The RAMPED Trial – It’s a Gas, Gas, Gas first appeared on The Skeptics Guide to Emergency Medicine. Reference: Brichko et al. Reference: Brichko et al. AEM Feb 2021.

Hyperthermia / Hypothermia 52

Hyperthermia / Hypothermia Emergency Department Administration Research 52

Don't Forget the Bubbles

NOVEMBER 15, 2023

One-liner… Understanding how to manage maintenance fluids in critically unwell children best is a basic but important way to improve outcomes. The REVERSE-AKI feasibility trial suggests that fluid restriction can improve outcomes without significant renal consequences. What do we need to give? PMID: 29589054; PMCID: PMC5924672.

Resuscitation 80

Resuscitation Dehydration Administration Shock 80

ACEP Now

AUGUST 22, 2023

Intravenous insulin shifts potassium into cells, thereby lowering serum potassium within an hour of administration. A Common Case Hypoglycemia following insulin administration for hyperkalemia is common, occurring in approximately one in six patients (about 17 percent). 5,6 However, the difference between strategies was 0.17

Emergency Department 52

Emergency Department Administration Outcomes Research 52

The Skeptics' Guide to EM

AUGUST 22, 2020

The US Federal Drug Administration (FDA) allowed for emergency development and use of rt-PCR assays, and dozens of companies released assay kits. Louis and a member of their Emergency Medicine Research Core. I consciously have tried to avoid contributing to the COVID-19 information overload.

Emergency Department 52

Emergency Department Academics Research Administration 52

The Skeptics' Guide to EM

JUNE 24, 2018

Lucas Silva is a 5th year medical student from Brazil (6-years program in Latin America) and a former Research Fellow in the Department of Emergency Medicine at the Mayo Clinic (Rochester, Minnesota). Outcomes: * Efficacy Outcomes: Reduction in pain score (through visual analog scale or any other pain asses.

Emergency Department 52

Emergency Department Administration Outcomes Research 52

EMDocs

OCTOBER 30, 2023

Background and Context Contrast-enhanced computed tomography (CECT) is of paramount importance in the emergency department (ED) due to its indispensable role in facilitating precise diagnostic outcomes. 3 A study of CT use trends in the ED has shown increasing use of CTs by almost 60% from 2005 to 2013. West J Emerg Med. 2017;18(5):835-845.

Radiology 99

Radiology Radiology Emergency Department Hospitals 99

Don't Forget the Bubbles

MAY 17, 2023

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Early Antibiotic Use and Neonatal Outcomes Among Preterm Infants Without Infections. Yu W, et al. Pediatrics. 2023 Apr 12:e2022059427. Strane D, et al. Pediatrics.

Pediatrics 72

Pediatrics X-Ray Interpretation Sepsis Fractures 72

Stop and Think

MAY 10, 2023

The next comment comes from an academic cardiologist who has a stellar record of publication—and is known for making cautious conclusions when leading observational research. So people try to do the best that seems possible using the tools available, such as administrative datasets, despite all the flaws. All of the above.

Academics 52

Academics Research Administration Wellness 52

RebelEM

MARCH 23, 2023

The primary outcome, hospital length of stay, was significantly shorter both before and after propensity score adjustment for the phenobarbital group. A broad range of variables were included that potentially influences treatment decisions and/or outcomes. and IM, and the physician was able to choose the method of administration.

Emergency Department 52

Emergency Department Burns Outcomes Hospitals 52

Dr. Smith's ECG Blog

FEBRUARY 8, 2015

There was a good outcome. We believe this represents a form of “toxicomythology” given the millions of doses of beta -blockers administered in the past to patients with hyperadrenergic states, and a paucity of evidence of adverse outcomes (12). University of Pittsburgh, Veterans Administration Medical Center, Pennsylvania 15240.

Seizures 52

Seizures Administration Outcomes Hospitals 52

RebelEM

JANUARY 23, 2023

Health care professional involved in patient management and outcome assessment was completely blinded. Clark S, Bock SA, Gaeta TJ, Brenner BE, Cydulka RK, Camargo CA; Multicenter Airway Research Collaboration-8 Investigators. The effectiveness of IV cetirizine was determined to be statistically non-inferior. J Allergy Clin Immunol.

Allergic Reactions 52

Allergic Reactions Anaphylaxis Emergency Department Urgent Care 52

RebelEM

DECEMBER 19, 2022

trying harder and longer knowing they are enrolled in this study) Use of two different models of defibrillators may negatively impact the internal validity of this pilot study Certain baseline characteristics were not balanced, such as: prehospital intubation and Epinephrine administration.

EMS 52

EMS CPR Shock Resuscitation 52

EM Literature of Note

JANUARY 9, 2022

The Annals of Emergency Medicine Podcast continues apace, with free monthly updates from the original research published in the journal: iTunes Link SoundCloud Link Likewise, the Annals of Emergency Medicine Journal Club has published several monthly installments: Predicting Outcomes in Pediatric Pneumonia: Are We Omnipotent or Incompetent?

Hyperthermia / Hypothermia 40

Hyperthermia / Hypothermia Stroke Emergency Department Outcomes 40

PHEM Cast

APRIL 10, 2016

And from our buddies at HEFT EM CAST: [link] A bit more detail covering some of the research in an easy to understand way. This was the same principle as in the Rivers trial: the standard care group is the ‘control’ group against which changes in outcome for the ‘intervention’ group are compared. 2006 Jun 3;332(7553):1295–8.

Sepsis 52

Sepsis Fluid Resuscitation Resuscitation Emergency Department 52