REBEL Core Cast 109.0 – Na Channel Blocker Poisoning
RebelEM
SEPTEMBER 27, 2023
Treatment is guided by administration of sodium-bicarbonate. If QRS >100 msec = 33% chance of seizures If QRS >160 msec = 50% of ventricular dysrhythmias Often extrapolated to other sodium channel blocking agents: diphenhydramine, loperamide, cocaine, lamotrigine, Type 1A/1C Anti-Dysrhythmics. Boehnert 1985 ). N Engl J Med.
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