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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Approximately 12 hours following F(ab’) 2 antivenom administration, the child is noted to have progressive swelling, firmness, tension, and pain of the right calf. On follow-up 1 week later, the patient was doing well, ambulating and playing without significant discomfort. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

antibiotics, NSAIDs) Acute urticaria with angioedema or anaphylaxis provided that urticaria was still present after initial treatment and alleviation of anaphylaxis symptoms. Exclusion: Presented with acute anaphylaxis, and their acute anaphylactic symptoms had not yet been treated. J Allergy Clin Immunol. PMID: 14767453.

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SGEM#188: Icatibant Bites the Dust – For ACE-I Induced Angioedema

The Skeptics' Guide to EM

Your resident tells you that they recently read an article in the NEJM that argued for the administration of icatibant to usher along resolution of symptoms in ACE-I induced angioedema and asks whether you should consider this treatment. Though this disorder is routinely treated with medications for anaphylaxis (i.e.

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52 in 52 – #36: Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

EMDocs

mg/kg or 10 mg Seizures must persist for at least 5 minutes after administration of the prespecified benzodiazepines. Study included children, as well as adults. In light of these data, I will give levetiracetam due to its less severe side effects and ease of administration. mg/kg or 10 mg Intravenous lorazepam 0.1

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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM

Cases of toxicity have been reported following ingestion of supplements as well as ingestion of willow bark tea [4,5]. However, most adverse reactions from willow bark supplements have been associated with people who have aspirin allergies, with numerous cases of anaphylaxis [6]. How does willow bark toxicity present? [7]

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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Early administration of antibiotics is the only factor known to reduce this mortality. Early administration of antibiotics is the only factor known to reduce this mortality. Cohort Study of the Impact of Time to Antibiotic Administration on Mortality in Patients with Febrile Neutropenia. Radiologypics, P. 2014, November 10).

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Vasopressor Nonresponse

Northwestern EM Blog

Due to its extremely high morbidity and mortality as well as high healthcare costs, the prompt recognition, diagnosis and resuscitation of shock is key. At those levels, bicarbonate administration has not been shown to improve cardiac output, MAP or pressor response. Anaphylaxis Anaphylaxis may present as hypotension alone.