Administration Allergic Reactions Research 
EMDocs
AUGUST 31, 2023
Approximately 12 hours following F(ab’) 2 antivenom administration, the child is noted to have progressive swelling, firmness, tension, and pain of the right calf. Research suggests that F(Ab’) 2 antivenom, compared against F(ab) antivenom, may be associated with lower rates of late and recurrent coagulopathy. 2016;8(1):113-119.
Emergency Live
AUGUST 19, 2024
FDA approved the first adrenaline-based nasal spray used to treat anaphylactic shock An epochal breakthrough in the management of severe allergic reactions has been announced by the US Food and Drug Administration (FDA).
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RebelEM
JANUARY 23, 2023
Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Resources: Banerji A, Long AA, Camargo CA Jr. Allergy Asthma Proc.
Pediatric Emergency Playbook
AUGUST 1, 2016
It’s not an allergic reaction: even with the old preparations of hyaluronidase, allergic reactions were rare, and now they are very rare with the recombinant preparation. in 2007 compared subcutaneous administration of lactated ringer’s solution by gravity with and without hyalurondase.
EB Medicine
DECEMBER 30, 2019
Emergency Department Treatment Oxygen Keep O2 saturation >90% Clinicians may choose not to use continuous pulse oximetry (weak recommendation due to low-level evidence and reasoning) 1 Fluids IV or NG administration of fluids to combat dehydration, until respiratory distress and tachypnea resolve. Racemic Epinephrine Not recommended 1.
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