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Clinical Conundrums: Should I Pretreat Patients with Contrast Allergy Prior to IV Contrast Administration?

RebelEM

Do you pretreat the patient prior to CT scan or proceed without delay and risk an allergic reaction? Administer the pretreatment medications as this should prevent any severe allergic reaction. The post Clinical Conundrums: Should I Pretreat Patients with Contrast Allergy Prior to IV Contrast Administration?

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Adrenaline nasal spray: the revolution against allergic shock

Emergency Live

FDA approved the first adrenaline-based nasal spray used to treat anaphylactic shock An epochal breakthrough in the management of severe allergic reactions has been announced by the US Food and Drug Administration (FDA).

Shock 52
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STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

RebelEM

neoplasm, aneurysm, intracranial or spinal surgery) or recent trauma to head or cranium (i.e. Primary PCI: 95.7% Stents Placed: Pharmaco-Invasive Treatment: 97.4% Primary PCI: 95.7% ECG Results: Repeat ECG 90min after tenecteplase indicated 70.3% to 1.0mm Median amount of ST deviations declined from 15.0 Primary PCI: 78.4% Primary PCI: 13.3%

EKG/ECG 137
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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Resources: Banerji A, Long AA, Camargo CA Jr. Allergy Asthma Proc. Ledford, D.

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Grand Rounds Recap 3.15.23

Taming the SRU

Yates Anaphylaxis Pathophysiology Type 1 Hypersensitivity Reaction IgE-mediated Mast-cell degranulation of vasoactive materials Reaction occurs in minutes Clinical Definition: Acute onset of illness with involvement of the skin, mucosal tissue or both + one of the following Respiratory compromise Reduced BP Or, acute onset of illness with at least (..)

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

Unfortunately, this myokymia may not respond to antivenom administration and myokymia of the chest well and torso can necessitate intubation in extreme cases. Nachi: In terms of respiratory effects of envenomations – they aren’t common. Both bites to the head or neck and neurotoxin containing venom are potential causes.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Approximately 12 hours following F(ab’) 2 antivenom administration, the child is noted to have progressive swelling, firmness, tension, and pain of the right calf. doi:10.1080/19420862.2015.1111497 Antivenom administration North American Crotalinae snakebites – UpToDate. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.