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Giving TXA Via An Intraosseous Line?

The Trauma Pro

The IV peak was higher than IO and approached statistical significance (0.053) ROTEM showed that the animals were significantly hyperfibrinolytic after injury, but rapidly corrected after administration of TXA. Results were the same for both IV and IO groups. Bottom line: This was a very simple and elegant study.

Military 279
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Eighteen Years as a Nocturnist: Night-shifters do it without even a little consideration from administration

Emergency Medicine News

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Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial

EM Ottawa

Findings: There was no statistically significant difference in median total 24hr blood product […] The post Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial appeared first on EMOttawa Blog.

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Nursing Malpractice: The Basics – Part 2

The Trauma Pro

Most people worry about common errors like wrong dose, wrong drug, and wrong route of administration. What are common sources of malpractice complaints against nurses? The most common event is medication error. But one less commonly considered drug-related responsibility is assessment for side effects and toxicity of medications administered.

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Thyroid Storm Management

Mount Sinai EM

Important, earlier administration may precipitate increased production of thyroid and worsening of storm. For esmolol, loading dose of 250 to 500 mcg/kg, followed by an infusion at 50 to 100 mcg/kg per minute OR a loading dose of 1 mg/kg over 30 seconds followed by approximately 150 mcg/kg/minute Thionamide – PTU preferred.

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Another Study on Peripheral Vasopressors

RebelEM

Historically the administration of vasopressors was restricted to central venous catheters (CVC) due to concerns for local tissue injury resulting from vasoconstriction if extravasation occurred from a peripheral IV. Peripheral Administration of Norepinephrine: A Prospective Observational Study. Paper: Yerke JR et al. CHEST 2024.

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ECG Blog #393 — Why So Many Shapes?

Ken Grauer, MD

Although this ultimately resulted in successful conversion to sinus rhythm — the immediate result of Adenosine administration caused the unusual rhythm discussed above ( seen in Figure-1 ). A DDENDUM ( 9/2/2023 ) : Adenosine was administered to today's patient for treatment of a regular SVT rhythm.

EKG/ECG 289