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"Sepsis bundles": No good evidence of benefit

PulmCCM

SEP-1, the Centers for Medicare & Medicaid Services (CMS)’s much-maligned sepsis “quality” measure, was the brainchild of a small group of insiders conceived in the early- to mid-2000s. SEP-1 was pushed through without waiting for the outcomes of three ongoing multicenter trials testing goal-directed therapy for sepsis.

Sepsis 52
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Sniffing out Sepsis - Vibes vs Scoring Systems?

Taming the SRU

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med 2024 Background Sepsis remains an increasingly common emergency department condition that is tied to higher morbidity and mortality across the United States as well as the rest of the world.

Sepsis 89
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Episode 7: Sepsis

PHEM Cast

[link] We hope you enjoyed our sepsis podcast. St Emlyns Induction podcast on Sepsis. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. March 2016.

Sepsis 52
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Is a Cuff Enough?

Taming the SRU

The surviving sepsis guidelines weakly recommend invasive arterial blood pressure monitoring (IABP) over noninvasive blood pressure monitoring (NIBP) with a blood pressure cuff supported by low quality evidence.(1) Surviving sepsis campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Sepsis 94
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HR24: Acute Inpatient Medicine – Next Level

Thinking Critical Care

So, while waiting for HR25 (May 2025), Katie once again worked her magic to put together a one-day webinar that packs a academic and clinical punch. Preliminary Schedule: H&R 2024 Outline: Acute Inpatient Medicine – Next Level! Date: June 15 10am-4:30pm EST (7am-1:30pm PST) Format: one-day, 6.5

Shock 63
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The 80th Bubble wrap x DFTB MSc in PEM

Don't Forget the Bubbles

The study included academic NICUs, which may reduce the generalisability of the results. Reviewed by: Tasnim Ransome and Spyridon Karageorgos Article 3: Which Sepsis Scoring Tools Perform Best? Organ Dysfunction in Children With Blood Culture-Proven Sepsis: Comparative Performance of Four Scores in a National Cohort Study.

Sepsis 75
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Diagnostics: Inflammatory Markers

Taming the SRU

A 2011 meta-analysis in the journal of Academic Emergency Medicine found ESR, CRP, and PCT were not acutely useful in the diagnosis of septic arthritis due to wildly varying sensitivities and specificities between studies. Sepsis PCT may have some utility in guiding posttest probability for sepsis when the diagnosis is unclear.