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Mandrola Chooses a Favorite Academic Article

Sensible Medicine

Words that pop into my head when thinking about the academic literature: vast, insipid, repetitive, Sisyphus. He had grown the once small Circulation--Cardiovascular Quality and Outcomes into a prominent journal in the academic cardiology space. This sentence came seven years before social media and a virus shredded our norms.

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Fear and Opioids in Academic Medicine

Sensible Medicine

From these reductions, whether they proceeded quickly or slowly, I saw terrible outcomes. To be clear, a substantial number of patients who reduce doses obtain good outcomes. Respect for the standards by which one is judged is adaptive in academic medicine. Later papers substantiated these warnings.

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Three Academics Speak Out on Bad Medical Studies

Stop and Think

You should first know Dan is one of the smartest and kindest academics I have met. It’s quite an honor to have legit academics comment on my Substack. My response: While I believe that academics have--as one goal—the discovery of answers to help our patients. Regarding outsized conclusions, I could not agree more.

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How Long Should EM Residency Be? New Studies Shed Light

ACEP Now

2,3 In the 2021-2022 academic year, categorical (non-combined) EM residency lengths included 221 (80 percent) PGY 1-3 and 55 (20 percent) PGY 1-4 programs. A fourth year of EM training offers additional supervised clinical and academic experience. Residency length has varied since the inception of the specialty of emergency medicine.

EMS 114
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When Studies Can't Answer an Important Question (but are still published)

Sensible Medicine

They then looked at a primary outcome of death. Earlier surgery may improve outcomes in these high-risk patients. Differences in baseline characteristics between the 2 groups likely largely explain the differences in their outcomes as discussed above, and propensity matching was not performed. vs 18.2% ; P =.036). I am asking.

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Can acetaminophen improve outcomes in sepsis?

PulmCCM

The ASTER Trial Ware et al conducted a phase 2b randomized trial from 2021 to 2023 among 447 patients admitted with sepsis and organ failure at 40 US academic hospitals. Patients received either 1 g of acetaminophen IV every six hours or placebo for five days.

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Fraud, Distortion, and Truth in Science

Sensible Medicine

The episode details examples of academic papers with fraud — the data were fabricated, and there were many tell tale signatures of fraud along the way. Most academics create causal conclusions that aren’t true. This week Freakonomics has an interesting podcast about science. It explores how and why this happens.

Academics 109