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Sniffing out Sepsis - Vibes vs Scoring Systems?

Taming the SRU

Population Patients were adult (18 or older) patients at a single academic emergency department who were triaged to a resuscitation bay and were not classified as a trauma, STEMI, stroke, cardiac arrest, or active labor. sensitivity, 84.9% specificity) and 60 minutes (85.1% sensitivity, 87.2% specificity).

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Sepsis alerts work! Just not in the patients who fire the alerts

PulmCCM

Rather, CMS should seek counsel from leaders in systems-based processes of care, teamed with frontline emergency physicians and intensivists from academic centers and the community, who could call for briefing and expertise from other sources as appropriate.

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Contrast Media Shortage of 2022 – Lessons Learned

EMDocs

Relative proportions of reported diagnostic indications versus clinical outcomes in a retrospective analysis of all CT imaging in 3 EDs over 1 year at an academic center. Under standard operating protocols, residual contrast materials are usually wasted, according to current CDC and JC standards. West J Emerg Med. 2017;18(5):835-845.

Radiology 101
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The Safety and Efficacy of Push Dose Vasopressors in Critically Ill Adults

RebelEM

They can be associated with side effects such as reflex bradycardia, decreased stroke volume in phenylephrine, tachycardia and hypertension associated with epinephrine. However, peripherally dosed push dose pressors, (PDPs), are beginning to be administered more frequently for management of acute hypotension.

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Grand Rounds Recap 7.31.24

Taming the SRU

The largest retrospective cohort study to date (Beyde et al.) shows that most will improve with empiric antibiotics.

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Diagnostics: Inflammatory Markers

Taming the SRU

A 2011 meta-analysis in the journal of Academic Emergency Medicine found ESR, CRP, and PCT were not acutely useful in the diagnosis of septic arthritis due to wildly varying sensitivities and specificities between studies. They recommend synovial joint aspiration and analysis for bacteria (and leukocytes) to diagnose SANJO [28].

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2024 Emergency Medicine Research Highlights: Forced Air, Sepsis, and More

ACEP Now

In a prospective study comparing clinician gestalt against systemic inflammatory response syndrome, Sequential Organ Failure Assessment (SOFA), quick SOFA, Modified Early Warning Score (MEWS), and a logistic regression machine learning model using Least Absolute Shrinkage and Selection Operator (LASSO), the obvious winner was the clinician.

Sepsis 40