Remove 2022 Remove Blood Transfusions Remove Stroke
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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 135
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emDOCs Podcast – Episode 100: Acute Chest Syndrome Part 1

EMDocs

Based on light absorption from blood flow at the sensor site (using HbA, not HbS) Underestimates alveolar hypoxemia. 2022 Aug;58:235-244. Epub 2022 Jun 11. Infectious: bacterial or viral pneumonia ( M. pneumoniae, C. All patients with ACS should receive antibiotics, as 25% have an infection as the trigger for ACS.

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emDOCs Podcast – Episode 101: Acute Chest Syndrome Part 2

EMDocs

Based on light absorption from blood flow at the sensor site (using HbA, not HbS). Blood transfusion Reduces the overall proportion of HbS. 2022 Aug;58:235-244. Epub 2022 Jun 11. Infectious: bacterial or viral pneumonia ( M. pneumoniae, C. Underestimates alveolar hypoxemia. Improves oxygen carrying capacity.

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ICU Physiology in 1000 Words: The Right Atrial Pressure Does Not Determine Cardiac Output – Part 2

PulmCCM

In the second thought experiment, let us consider a patient with significant blood volume loss that is replenished with a series of blood transfusions. For any given hemodynamic state, measure or estimate the P ra and CO [or stroke volume, SV] simultaneously and repeatedly after each intervention. What does this mean?

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Issue #1: The Latest in Critical Care, 5/8/23

PulmCCM

Read in JAMA Endovascular thrombectomy for large ischemic stroke came to prominence based on limited data showing its efficacy in patients with smaller strokes; large strokes were excluded. This was a noninferiority trial; remifentanil fell below the prespecified threshold for inferiority, though with a wide confidence interval.

Stroke 52
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Grand Rounds Recap 3.29.23

Taming the SRU

Cardiac Arrest in Pregnancy 1 in 30,000 pregnancies 800 maternal deaths globally Rates have nearly doubled between 1989 and 2009 Survival to hospital discharge after maternal in-hospital cardiac arrest 58.9%

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Subarachnoid hemorrhage: ED presentation, evaluation, and management

EMDocs

National Institutes of Health Stroke Scale (NIHSS) is 13; vital signs include pulse 86 beats/minute (bpm), blood pressure 164/94 mmHg, and saturation of 98% on room air. 14 The American Stroke Association (ASA) and American Heart Association (AHA) recommend SBP <160 mmHg until definitive management of the bleed is completed.