EMDocs

JUNE 27, 2024

His medical history is significant for three prior admissions for vaso-occlusive crises that have responded well to appropriate therapy, including pain control with NSAIDs and opioids, blood transfusions, antibiotics, and intravenous (IV) crystalloids. 2022 Jul 5;328(1):57-68. 2022 Aug;58:235244. Epub 2022 Jun 11.

Pediatrics 76

Pediatrics Dehydration EMS Hospitals 76

PulmCCM

MAY 8, 2023

Among 324 patients with trauma and life-threatening bleeding at 12 French hospitals who were randomized to receive 1ml/kg PCC or placebo, there was no reduction observed in 24-hour blood transfusion needs in the PCC group. PCC was associated with a significantly higher risk for thromboembolic complications (35% vs 24%).

Stroke 52

Stroke Hospice Blood Transfusions Anaphylaxis 52

Don't Forget the Bubbles

NOVEMBER 18, 2024

Research and guidelines from Australian centres, like those published by the Australian and New Zealand Neonatal Network (ANZNN), emphasize early detection and management to improve outcomes. If anaemia is confirmed, a blood transfusion may be necessary to restore adequate circulatory volume and improve oxygen-carrying capacity.

Sepsis 59

Sepsis Shock Hyperthermia / Hypothermia Administration 59

Northwestern EM Blog

JANUARY 24, 2022

Those at higher risk of hypocalcemia (vitamin D deficiency, ESRD, hyperparathyroidism, burns, multiple blood transfusions, etc.) However, even subclinical hypothyroidism with an elevated TSH but normal T4 increases risk of poor outcomes due to effects on cardiac function. 2022, Jan 24). Understanding adrenal crisis.

Anaphylaxis 52

Anaphylaxis Shock Sepsis Resuscitation 52

EMDocs

JUNE 3, 2023

Published November 8, 2022. Published April 22, 2022. Management and outcomes of open pelvic fractures: An update. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Radiopaedia.org.

Fractures 54

Fractures Resuscitation Operations EMS 54

RebelEM

FEBRUARY 1, 2024

What they Did : Investigator-initiated, Multicenter, Parallel-ground, Open-label, Registry-linked, Randomized, Controlled, Non-Inferiority trial 22 Canadian Primary and Comprehensive Stroke Centers from December 2019 to January 2022 Eligible ischemic stroke patients randomized 1:1 to receive intravenous tenecteplase (0.25 vs Alteplase 34.8%

Stroke 133

Stroke Blood Transfusions Outcomes EMS 133

Don't Forget the Bubbles

OCTOBER 28, 2024

To address this, there is ongoing debate about whether we should consider using a whole blood transfusion approach. Rhaenyra continues to receive blood products in a 1:1:1 ratio. In adults, TXA has been shown to reduce transfusion requirements and improve outcomes. Published 2022 May 4. 2022 Apr 22;8(1):25.

Blood Transfusions 72

Blood Transfusions Hyperthermia / Hypothermia Shock Pediatrics 72

EMDocs

MARCH 6, 2024

There is no clear improvement with idarizucimab or andexanet alfa on patient-oriented outcomes. TXA: Several studies have found no benefit in patient-oriented outcomes with TXA in patients with significant lower GI bleeding. Red Blood Cell Transfusion: 2023 AABB International Guidelines. 2022 May 2;5(5):e2214253.

Blood Transfusions 86

Blood Transfusions Outcomes Resuscitation Radiology 86

EMDocs

JULY 3, 2023

Introduction SAH has the potential for rapid progression and devastating outcomes. Hematoma expansion Reducing blood pressure to a level that limits bleeding but maintains perfusion is critical to limit hematoma expansion, especially in spontaneous SAH. 2022 Jan;39(1-2):35-48. Blood Transfus. J Neurotrauma.

Seizures 86

Seizures Stroke Outcomes EMS 86