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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Background: Sepsis remains one of the leading causes of morbidity and mortality. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. Health Sci Rep 2022. Until that time, the best evidence indicates that in the sickest patients (i.e. to 0.97; p = 0.02

Sepsis 132
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The 90th Bubble wrap DFTB X The Bridge

Don't Forget the Bubbles

Reviewed by Dr Faye Leggott Article 2: Does fluid overload increase mortality in children with sepsis? Association between fluid overload and mortality in children with sepsis: a systematic review and meta-analysis. Sepsis is a significant cause of mortality in children, and fluid resuscitation is a key treatment strategy.

Sepsis 59
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emDOCs Podcast – Episode 89: Antibiotics for Uncomplicated Diverticulitis

EMDocs

Included patients had confirmed uncomplicated diverticulitis but no immunosuppression, peritonitis, sepsis. Patients with sepsis and immunocompromise were not included. Open-label, non-inferiority RCT including patients with uncomplicated diverticulitis, no significant comorbidities, no immunosuppression, and no signs of sepsis.

Sepsis 113
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First10EM Journal Club: June 2023

Broome Docs

This episode covers herbs that may heal sepsis, drugs that probably don’t help in Covid, we ask: do steroids help in pneumonia? Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis: The EXIT-SEP Randomized Clinical Trial. BMJ Best Practice. 2022 Aug;48(8):1009-1023. JAMA Intern Med.

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Diagnostics: Blood Transfusion Reactions

Taming the SRU

10, 19 May 2022, p. 2, July 2022, pp. Taming the SRU , www.tamingthesru.com/clinical-practice-guidelines. Adverse reactions to transfusion of blood products and Best Practices for Prevention.” 2859, [link] Afroz, Tamanna, et al. Global Journal of Transfusion Medicine , vol. 169–173, [link] Aubron, C.,

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emDOCs Podcast – Episode 88: ED Evaluation of Diverticulitis

EMDocs

American Gastroenterological Association (2021) Best Practice Advice 1: Computed tomography should be considered to confirm the diagnosis of diverticulitis in patients without a prior imaging-confirmed diagnosis and to evaluate for potential complications in patients with severe presentations. 2022 Mar;175(3):399-415.

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Antibiotics in the paediatric emergency department

Don't Forget the Bubbles

This is true in life-threatening conditions such as sepsis. However, when children do not have features of sepsis, oral antibiotics are equally effective. The take home is that although IV antibiotics are key in sepsis management, oral antibiotics are equally as effective as IV antibiotics for children without critical illness.