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Allergic Reactions and Anaphylaxis

EB Medicine

Announcements: The interactive Clinical Pathways have launched and they are available for free! — In this episode, Sam Ashoo, MD, and TR Eckler, MD, discuss the July 2022 Emergency Medicine Practice article on the Management of Allergic Reactions and Anaphylaxis in the Emergency Department. Intro The number of ED visits and hospitalizations (..)

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EM@3AM: Leukopenia

EMDocs

Philadelphia, PA: Elsevier; 2022:1-11. 101,33 (2022): e30116. Updated 2022 Nov 14]. Answer : Leukopenia Overview Leukopenia is defined as total WBC count < 4000/mm 3 Neutropenia is the most common subset of leukopenia and is defined on absolute neutrophil count: 1 Mild (1.01.5 10^9/L) Moderate (0.50.9 Medications: 25.6%

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Pediatric Balanitis and Balanoposthitis

Pediatric EM Morsels

Balanitis and Balanoposthitis – Basics Terminology [Assim 2022, Dynamedex 2024, Perkins 2024] Balanitis – Inflammation of the glans penis Posthitis – Inflammation of the foreskin (prepuce) Balanoposthitis – Inflammation of both (ouch!)

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Accessed May 7, 2022. Accessed May 7, 2022. Accessed May 7, 2022. Accessed May 7, 2022. StatPearls Publishing; 2022. Accessed May 17, 2022. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms. References: Ubani C, DeGelorm A, Sollee D. Poison Control: The F(ab2)ulous Expanded Indication of Anavip | FCEP.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

American Gastroenterological Association issued a practice guideline in November 2022 recommending that semaglutide 2.4 Retrospective study published in 2022 of 81,752 adverse events associated with GLP-1 agonist therapy found an increased risk of pancreatitis, particularly with liraglutide (ROR 32.67; 95% CI 29.44-36.25).

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The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

RebelEM

What They Did: Parallel, 2-arm, noninferiority, open-label, multicenter, international randomized clinical trial Occurred in 6 specialized centers (3 in North America – US & Canada and 3 Outside of North America – Australia) Trial took place from June 2021 to December 2022 Used PEN-FAST to risk stratify patients.

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CT Angiography Head and Neck: Indications and Limitations

EMDocs

An understanding of the risks involved including allergic reaction, radiation exposure, contrast extravasation, and contrast-associated nephropathy allows for a thorough risk-benefit analysis prior to ordering these studies. American Journal of Roentgenology 2022, 218 (3), 544-551. Emerg Radiol 2022, 29 (2), 291-298.

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