Remove 2021 Remove Hyperthermia / Hypothermia Remove Seizures
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ToxCard: Second Generation Antipsychotic Overdose

EMDocs

of exposures reported to poison control centers in 2021 were related to antipsychotics or sedative-hypnotics with the majority of those exposures occurring in patients 20 years of age or older. 1 Seizures may occur due to lowered seizure threshold. 6 Seizures have been observed and are dose-dependent. Front Psychiatry.

Poisoning 111
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Leading Change | IN Midazolam Seizure | Hypothermia Infant Sepsis | VICTAS RCT | GHB Dx

JournalFeed

It’s the JournalFeed Podcast for the week of Apr 19-23, 2021. We cover leadership through change, IN midazolam for pediatric seizure, hypothermia and young infant sepsis risk, VICTAS RCT, and clinically diagnosing GHB intoxication.

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Congenital Syphilis

Pediatric EM Morsels

We have previously discussed hypothermia presentations , GBS infections , and HSV infections. 2019, there were 1,875 and this trend has continued to increase (2,157 case in 2020; 2,855 cases in 2021). 2021 Feb 5;14(2):e240532. Fortunately, we have addressed many neonatal issues in the PedEMMorsels. 2022 Dec 27;14(12):e33009.

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ToxCard: Anticholinergic Plant Toxicity

EMDocs

3-6 Clinical Presentation: Symptoms include altered mental status, tachycardia, hyperthermia, urinary retention, mydriasis, blurred vision, dry skin, hallucinations. Anticholinergic toxicity has overlap with other toxicological causes of hyperthermia which are reviewed here: Hyperthermia in the Toxicological Setting.

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Super Refractory Status Epilepticus

Don't Forget the Bubbles

Four-year-old Fern is a previously healthy girl who presents with a febrile illness and seizures. Seizure activity did not respond to either first or second-line treatments, so she needed rapid sequence induction and transfer to PICU for ongoing anaesthesia and management. What causes Super Refractory Status Epilepticus?

Seizures 111
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Major Trauma – Injuries by Assault

Don't Forget the Bubbles

Other considerations in significant TBI would be the temporary use of anti-epileptic drugs as prophylaxis to prevent early post-traumatic seizures to aid neuroprotection; the most commonly used would be levetiracetam. Disability – Altered mentation, seizure, stroke symptoms, severe headache, neurological deficit, visual symptoms.

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First10EM Journal Club: October 2022

Broome Docs

Epub 2021 Dec 14. Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial. 2022 Jul 26:emermed-2021-211540. doi: 10.1136/emermed-2021-211540. Intensive Care Med.