Diagnostics: Inflammatory Markers
Taming the SRU
AUGUST 30, 2023
However, PCT can be elevated in severe trauma, such as burns or surgery [5,25]. Despite these results, the 2021 Surviving Sepsis guidelines recommend against using PCT to guide initiation of antimicrobial therapy due to multiple meta-analyses demonstrating no improvement in outcomes using PCT-guided antibiotic therapy [46,54].
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