2021 Blood Transfusions Outcomes 
RebelEM
MAY 25, 2023
vs 3U) but no difference in mortality (Study not powered for this outcome) Clinical Take Home Point: The use of vasopressors is controversial and requires a nuanced approach SUMMARY OF MINIMIZING IATROGENIC INJURY RESTORE PERFUSION VOLUME REPLACEMENT Blood Products >>> Crystalloids Holcomb JB et al. NEJM 1994. [2]
RebelEM
DECEMBER 23, 2024
Within this population, over 90% of healthcare encounters are due to painful vaso-occlusive episodes (VOE) ( Kidwell 2021 ). The enrollment was multicenter, large, and adequately powered for clinically meaningful changes in outcome. Lactated Ringer (LR) and 0.9% Cross-validation was performed.
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Don't Forget the Bubbles
JANUARY 10, 2024
Transfusion Decisions in Severe Anaemia Reducing child mortality remains high on the global health agenda. Let’s take the humble blood transfusion – used in emergency departments across the globe and playing a key role in critical care. However, there is a huge variation in transfusion practice globally.
PulmCCM
NOVEMBER 6, 2023
patients infected with the Wuhan/Delta variants in 2020-2021). I recall very well my (unjustified) negative view on convalescent plasma in 2020 and 2021 — it was probably minimally effective, and I would never spontaneously offer it. Thromboelastometry (e.g., The balloon generally required 30 minutes to insert.
EMDocs
JUNE 12, 2024
HypoCa is common in trauma patients and is associated with poor outcomes. A meta-analysis found that 56% of patients with severe trauma resulting in hypotension have hypoCa.There was an increase in mortality, increased need for transfusion, and increased risk of coagulopathy in patients with hypoCa. 2021 Mar;41:104-109.
Don't Forget the Bubbles
JANUARY 1, 2024
Data collected from 2002 to 2021 revealed a 72% decline in IPD incidence among children (<18 years), with continued reductions after the transition from PCV7 to PCV13. During the COVID-19 pandemic (2020-2021), the incidence of IPD reached its lowest level in 20 years. Outcomes From a Randomized Clinical Trial. JAMA Pediatr.
PulmCCM
JANUARY 13, 2025
However, large observational cohorts have associated greater degrees of anemia with worse outcomes in patients with cardiac disease. In MINT, 3,504 patients with acute myocardial infarction and anemia were randomized to either a transfusion threshold of ≤8 g/dL, or a liberal transfusion threshold of ≤10 g/dL.
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