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Diagnostics: Blood Transfusion Reactions

Taming the SRU

In the era of modern medicine, blood transfusions are commonplace, especially in the emergency department. Transfusion reactions are a spectrum of adverse events that can occur with the transfusion of whole blood or any of its components. One of the major risk factors is receiving a blood transfusion in the past.

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Imported Malaria

Pediatric EM Morsels

This allowed US hospitals to stock the drug to ensure quick treatment of suspected severe cases, rather than having to ship it from the CDC under the prior expanded-access protocol (Thomas 2023). Travel Medicine and Infectious Disease 44 (2021) 102196. falciparum parasitemia , and no other defined cause of AMS (WHO 2023). J Travel Med.

Seizures 281
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Trauma Resuscitation Updates

RebelEM

Lancet 2010 [10] >20,000 adult trauma patients with SBP <90mmHg Patients randomized to TXA 1g over 10 min + 1g IV over 8hrs vs Placebo given within 8hrs of injury In-hospital mortality by 28d reduced (14.5% NEJM 1994. [2] NEJM 1994. [2] Richards JE et al.

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The Latest in Critical Care, 1/8/23 (Issue #24)

PulmCCM

Smaller blood-collection tubes to reduce red blood cell transfusion (STRATUS trial) Cumulatively, daily labs on hospitalized patients deplete substantial volumes of blood, almost all of which is wasted. mL per sample, and the rest is discarded. By one estimate, 25 million liters (6.6

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Are we on the right TRACT? 

Don't Forget the Bubbles

Let’s take the humble blood transfusion – used in emergency departments across the globe and playing a key role in critical care. Severe anaemia is a common and life-threatening cause of hospital admission in children in sub-Saharan Africa. 8% die in hospital, with a further 12% dying in the six months following discharge.

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emDOCs Podcast – Episode 102: Hypocalcemia in Trauma and the Diamond of Death

EMDocs

2021 Mar;41:104-109. 2021 Feb 1;90(2):396-402. A review of transfusion- And trauma-induced hypocalcemia: Is it time to change the lethal triad to the lethal diamond? Concentration-Dependent Effect of Hypocalcaemia on Mortality of Patients with Critical Bleeding Requiring Massive Transfusion: A Cohort Study. Li K, Xu Y.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

Blood Coagul Fibrinolysis. 2021 Jan 1;32(1):37-43. Four level-1 US trauma centers participated in the study where the inclusion criteria were trauma patients who were within 2 hours of their injury and were transported to the trauma center from either the field or another hospital. Rivas L, Estroff J, Sparks A, et al.