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Allergic Reactions and Anaphylaxis
EB Medicine
JANUARY 17, 2023
Intro The number of ED visits and hospitalizations Studies show up to 57% of anaphylactic reactions are not recognized, and epinephrine is not administered in up to 80% of cases.
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Steroid and Allergy
Emergency Medicine Education
AUGUST 10, 2024
Biphasic anaphylaxis: A review of the literature and implications for emergency management Corticosteroids in management of anaphylaxis; a systematic review of evidence
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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?
RebelEM
DECEMBER 5, 2023
While the evidence is not strong, those who have been undertreated, experienced delays in treatment, or required multiple injections of epinephrine are more prone to experience a recurrence of symptoms ( Ellis 2007 , Liu 2020 ). Updated Anaphylaxis Guidelines (2020) References Lieberman P. Biphasic Anaphylactic Reactions.
EM@3AM: Leukopenia
EMDocs
JANUARY 25, 2025
BioMed Research International, 2020, 1-10. Answer : Leukopenia Overview Leukopenia is defined as total WBC count < 4000/mm 3 Neutropenia is the most common subset of leukopenia and is defined on absolute neutrophil count: 1 Mild (1.01.5 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. link] Lu, W.,
Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED
RebelEM
JANUARY 23, 2023
Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Ann Emerg Med 2020. While the need for parenteral therapy is apparent in anaphylaxis, it’s more nebulous in minor and moderate non-life-threatening reactions such as urticaria.
EM@3AM: Traumatic Iritis
EMDocs
JUNE 8, 2024
Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergic reaction. McGraw Hill, 2020. Close follow-up within 48 hours with an ophthalmologist is appropriate for ongoing monitoring and care. and John O.
emDOCs Podcast – Episode 94: GLP-1 Agonist Complications
EMDocs
FEBRUARY 7, 2024
Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. 2020 Apr;46(2):100-109. Diabetes Metab. Davidson MH. Am J Cardiol. Gallwitz B.
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