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Allergic Reactions and Anaphylaxis

EB Medicine

Intro The number of ED visits and hospitalizations Studies show up to 57% of anaphylactic reactions are not recognized, and epinephrine is not administered in up to 80% of cases.

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EM@3AM: Leukopenia

EMDocs

BioMed Research International, 2020, 1-10. Answer : Leukopenia Overview Leukopenia is defined as total WBC count < 4000/mm 3 Neutropenia is the most common subset of leukopenia and is defined on absolute neutrophil count: 1 Mild (1.01.5 10^9/L) Moderate (0.50.9 10^9/L) Severe (< 0.5 10^9/L) Generalized leukopenia (i.e. link] Lu, W.,

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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

While the evidence is not strong, those who have been undertreated, experienced delays in treatment, or required multiple injections of epinephrine are more prone to experience a recurrence of symptoms ( Ellis 2007 , Liu 2020 ). Updated Anaphylaxis Guidelines (2020) References Lieberman P. Biphasic Anaphylactic Reactions.

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Steroid and Allergy

Emergency Medicine Education

Biphasic anaphylaxis: A review of the literature and implications for emergency management Corticosteroids in management of anaphylaxis; a systematic review of evidence

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Published online November 2020. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms. 9 This effect may be especially prominent in the setting of rattlesnake envenomation, where coagulopathic effects are more prominent. Influence of molecular size on tissue distribution of antibody fragments. 2016;8(1):113-119. Accessed May 7, 2022.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Ann Emerg Med 2020. While the need for parenteral therapy is apparent in anaphylaxis, it’s more nebulous in minor and moderate non-life-threatening reactions such as urticaria.

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EM@3AM: Traumatic Iritis

EMDocs

Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergic reaction. McGraw Hill, 2020. Close follow-up within 48 hours with an ophthalmologist is appropriate for ongoing monitoring and care. and John O.

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