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Allergic Reactions and Anaphylaxis

EB Medicine

Intro The number of ED visits and hospitalizations Studies show up to 57% of anaphylactic reactions are not recognized, and epinephrine is not administered in up to 80% of cases.

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Steroid and Allergy

Emergency Medicine Education

Biphasic anaphylaxis: A review of the literature and implications for emergency management Corticosteroids in management of anaphylaxis; a systematic review of evidence

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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

While the evidence is not strong, those who have been undertreated, experienced delays in treatment, or required multiple injections of epinephrine are more prone to experience a recurrence of symptoms ( Ellis 2007 , Liu 2020 ). Updated Anaphylaxis Guidelines (2020) References Lieberman P. Biphasic Anaphylactic Reactions.

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Garlic for Ear Infections?

Pediatric Education

Known side effects: Pungent breath and body odor Nausea/dyspepsia Allergic reactions Skin irritant and burns (especially if used crushed/cut bulb is used under occlusion) – raw garlic should not be used on any skin surface because of the risk of irritation/burn Drug interference – can possible potentiate the drugs effects (i.e.

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EM@3AM: Traumatic Iritis

EMDocs

Dilation of conjunctival vessels resulting in hyperemia and edema (A) is the underlying pathophysiology of conjunctivitis, which can be brought on by infection or allergic reaction. McGraw Hill, 2020. Close follow-up within 48 hours with an ophthalmologist is appropriate for ongoing monitoring and care. and John O.

EMS 80
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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. 2020 Apr;46(2):100-109. Diabetes Metab. Davidson MH. Am J Cardiol. Gallwitz B.

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Nephrotic Syndrome

Mind The Bleep

Steroid resistance Failure to achieve complete remission after 8 weeks of prednisolone at 60mg/m2/day Differentials Heart failure – would present with oedema, shortness of breath, cyanosis Allergic reaction – presents with facial oedema, pruritus. Paediatric Nephrology , 1409-1418. Daehn IS, D. Goyal S, D. Goyder K, H.