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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 131
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Subarachnoid hemorrhage: ED presentation, evaluation, and management

EMDocs

National Institutes of Health Stroke Scale (NIHSS) is 13; vital signs include pulse 86 beats/minute (bpm), blood pressure 164/94 mmHg, and saturation of 98% on room air. 14 The American Stroke Association (ASA) and American Heart Association (AHA) recommend SBP <160 mmHg until definitive management of the bleed is completed.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

Lancet 2019; Vol 394, Iss 10210, P 1713-1723[ Full Text ]. MI or stroke). TXA does not increase the incidence of thromboembolic events such as DVT/PE, stroke, or MI. Bossers SM, Loer SA, Bloemers FW, et al. Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury.

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Sickle Cell Disease Module

Don't Forget the Bubbles

The Kilifi algorithm includes five clinical situations that are common sickle cell presentations – clinical jaundice, severe anaemia, bone and joint infections, and stroke. Newborn screening: sickle cell screening is donethrough heel-prick blood at five days of life. Would you consider this patient for blood transfusion?