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The Latest in Critical Care, 1/8/23 (Issue #24)

PulmCCM

million gallons) of blood are wasted in this fashion, every year—enough to fill about 700 railroad tanker cars with blood, or about four times the total amount of blood transfused annually. Smaller-volume blood collection tubes are widely available at equivalent cost and are compatible with standard blood analyzers.

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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

What they Did : Investigator-initiated, Multicenter, Parallel-ground, Open-label, Registry-linked, Randomized, Controlled, Non-Inferiority trial 22 Canadian Primary and Comprehensive Stroke Centers from December 2019 to January 2022 Eligible ischemic stroke patients randomized 1:1 to receive intravenous tenecteplase (0.25 vs Alteplase 34.8%

Stroke 134
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There will be blood

Intensive Blog

What is an appropriate “trigger threshold” for blood transfusion in ECMO patients? Blood transfusion is common in ECMO patients, as evidenced by almost 90% of all patients receiving at least one packed red blood cell transfusion during VV-ECMO support (Kalbhenn and Zieger, 2022). 2020.08.068.

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Imported Malaria

Pediatric EM Morsels

Both have a range of detection limits, which can be greatly dependent on operator. 2019; 17: 98. 2019; 47(2): 183–193. 3 thick and thin smears should be obtained at 12-24 hour intervals to fully rule out the possibility of malaria PCR is the most sensitive and specific test for malaria. Pediatr Clin N Am 69 (2022) 47–64.

Seizures 277
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Is there Wenckebach? An Elderly Patient with a Fall

Dr. Smith's ECG Blog

However, on occasion — dual AV nodal pathways physiology may be operative ( Mani BC & Pavri BB: Dual AV Nodal Pathways Physiology — Indian Pacing Electrophysiol 14[1]:12-25, 2014 ). As a result — all that may be needed is consideration of blood transfusion + efforts to determine ( and correct ) the cause of anemia.

EKG/ECG 52
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Unstable Pelvic Trauma Patient: ED Presentations, Evaluation, and Management

EMDocs

4 Patients with pelvic fractures are considered unstable when systolic blood pressure < 90mmHg and heart rate >120bpm, or in those with dyspnea, altered mental status, or skin findings of shock. 13 Massive transfusion protocols (MTP) are hallmarks of trauma resuscitation, and they are critical to the unstable pelvic fracture patient.

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Sickle Cell Disease Module

Don't Forget the Bubbles

Be careful if the patient has received a recent blood transfusion since it may be misinterpreted as sickle cell trait instead of sickle cell disease. In these cases, repeat the Hb electrophoresis three months after the last blood transfusion. Would you consider this patient for blood transfusion?