Balanced solutions: better than saline, but which balanced solution?
PulmCCM
FEBRUARY 27, 2025
But researchers at Vanderbilt, where the SMART study testing balanced crystalloids was performed , checked—just to be sure. As a comparison, the SMART trial ( NEJM 2018 ), performed at five ICUs at Vandy, enrolled 16,000 subjects to find meaningful clinical differences between balanced solutions and normal saline. 2025.02.008.
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