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Super Refractory Status Epilepticus

Don't Forget the Bubbles

Four-year-old Fern is a previously healthy girl who presents with a febrile illness and seizures. Seizure activity did not respond to either first or second-line treatments, so she needed rapid sequence induction and transfer to PICU for ongoing anaesthesia and management. What causes Super Refractory Status Epilepticus?

Seizures 111
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Cannabidiol in refractory status epilepticus

Don't Forget the Bubbles

A UK-based study found that 4% of admissions to a tertiary paediatric intensive care unit (PICU) over a 10-year period were due to refractory status epilepticus (RSE) – seizures which fail to terminate despite appropriate first and second-line treatments. Despite this, the CFAM still showed ongoing electrical seizure activity.

Seizures 122
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SGEM#239: Febrile Seizure Recurrence – With or Without You Acetaminophen?

The Skeptics' Guide to EM

Date: December 13th , 2018 Reference: Murata et al. Acetaminophen and febrile seizure recurrences during the same fever episode. Pediatrics. 2018 Guest Skeptic: Dr. Damian Roland is a Consultant at the University of Leicester NHS Trust and Honorary Associate Professor for the University of Leicester’s SAPPHIRE group.

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Fluoroquinolone Use In Children

Pediatric EM Morsels

Jackson 2016) A systematic review of safety data for over 16000 pediatric patients did show MAEs were the most frequently reported event. 451 pediatric patients were included. Wirth 2018) One study including 4.4 Meesters 2018) Resistance is growing (likely from inappropriate / overuse)! Pediatrics. Clin Pediatr.

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TXA in head injuries

Don't Forget the Bubbles

As in CRASH-2, TXA did not show a significant increase in thrombotic events or seizures. published in 2018, looked at 1900 matched pairs of injured children under 12, half of whom received TXA. Tranexamic acid administration to pediatric trauma patients in a combat setting: the pediatric trauma and tranexamic acid study (PED-TRAX).

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Congenital Syphilis

Pediatric EM Morsels

Foles, 2024 ] In the US, from 2013-2018, cases increased from 362 to 1,306. The post Congenital Syphilis appeared first on Pediatric EM Morsels. Worldwide, congenital syphilis complicates about 1 million pregnancies / year. Hussain, 2023 ] Leads to >300,000 perinatal deaths / year globally. A case of congenital syphilis.

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Mastering Minor Care: Concussion

Taming the SRU

For pediatric patients, we recommend using the PECARN Pediatric Head Injury Algorithm. Admission should also be strongly considered in patients with a depressed GCS, post-traumatic seizure(s), or intractable symptoms [2]. JAMA Pediatr. For high-risk patients, a non-contrast CT Head is the test of choice. JAMA Netw Open.