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What Are the Complications of Sickle Cell Trait?

Pediatric Education

He had no concerns and he was doing well in school and with his friends. He had a sprained ankle the previous year that he says was well-healed. With your sickle cell trait you usually shouldn’t have any problems, but dehydration could cause problems for you. The past medical history was positive for sickle cell trait.

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EM@3AM: Sialadenitis

EMDocs

Risk factors include oral neoplasms, sialolithiasis, advanced age, dehydration, ductal foreign bodies, concomitant tracheostomy, and recent receipt of an anesthetic agent. Published 2018 Nov 15. Patients who are immunocompromised may experience infection related to gram-negative organisms (e.g., J Clin Imaging Sci. 2020;64:87-104.

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emDOCs Revamp – Acute Chest Syndrome

EMDocs

His medical history is significant for three prior admissions for vaso-occlusive crises that have responded well to appropriate therapy, including pain control with NSAIDs and opioids, blood transfusions, antibiotics, and intravenous (IV) crystalloids. 2018 Aug;46(3):144-151. Epub 2018 Oct 17. C or 100.4 mg/kg, max 0.4

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Maintenance Fluids in Critical Illness

Don't Forget the Bubbles

As well as requesting relevant investigations and reviewing her drugs, you send paired urine and serum electrolytes to calculate a fractional excretion of sodium to categorise the cause as pre-renal vs other (see [link] for more information). 2018 Apr;44(4):409-417. Epub 2018 Mar 27. Intensive Care Med.

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SGEM#254: Probiotics for Pediatric Gastroenteritis – I Can’t Go For that…No Can Do

The Skeptics' Guide to EM

NEJM 2018 Guest Skeptic: Dr. Anthony G. NEJM 2018 Guest Skeptic: Dr. Anthony G. She is otherwise well appearing and has normal vitals and examines normally. Date: April 16th, 2019 Reference: Schnadower et al. Lactobacillus rhamnosus GG versus placebo for acute gastroenteritis in children.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Multiple well-designed, multicenter, multinational studies suggest GLP-1 agonists are associated with improved glucose control in diabetes type 2 and approximately a 15% reduction in weight over 1-2 years (around 2/3s of patients regain weight if treatment is stopped). 2018 Apr 17;319(15):1580-1591. Obesity affects over 40% of U.S.

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Sickle Cell Disease Module

Don't Forget the Bubbles

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Infections, fever, acidosis, hypoxia, dehydration and exposure to extreme temperatures can trigger VOC even though often no cause is identified. 2014; 349–356.