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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Background: Sepsis remains one of the leading causes of morbidity and mortality. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. Until that time, the best evidence indicates that in the sickest patients (i.e. Health Sci Rep 2022. to 0.97; p = 0.02

Sepsis 130
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emDOCs Podcast – Episode 89: Antibiotics for Uncomplicated Diverticulitis

EMDocs

Included patients had confirmed uncomplicated diverticulitis but no immunosuppression, peritonitis, sepsis. Patients with sepsis and immunocompromise were not included. 2018 Jul;113(7):1045-1052. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br  Br J Surg. 2012 Apr;99(4):532-9.

Sepsis 108
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Diagnostics: Blood Transfusion Reactions

Taming the SRU

Adverse reactions to transfusion of blood products and Best Practices for Prevention.” Mild Reactions Transfusion Reaction Frequency Timeline Presentation Management Allergic - 1-3% with platelet and plasma components - 0.1-0.3% 2, July 2022, pp. 169–173, [link] Aubron, C., Transfusion Clinique et Biologique , vol. Accessed 8 Sept.

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emDOCs Podcast – Episode 88: ED Evaluation of Diverticulitis

EMDocs

A 2018 risk score incorporates the presence of abdominal guarding, WBC, and CRP. Those with abdominal guarding, WBC over 20,000, and CRP over 25 mg/dL demonstrated a risk of complicated diverticulitis of over 85% (Bolkenstein 2018). 2018 Oct 2;14:1847-1853. 2018 Oct-Nov;53(10-11):1291-1297. Ther Clin Risk Manag.

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Antibiotics in the paediatric emergency department

Don't Forget the Bubbles

This is true in life-threatening conditions such as sepsis. However, when children do not have features of sepsis, oral antibiotics are equally effective. The take home is that although IV antibiotics are key in sepsis management, oral antibiotics are equally as effective as IV antibiotics for children without critical illness.

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The Latest in Critical Care, 3/11/24 (Issue #33)

PulmCCM

Each hospital’s Medical Executive Committee approved the protocol, and data was collected 2016-2018. I had never heard of this practice before. (To To be extra clear, these are not “best practice” alerts or prompts to suggest using an order set. The trial was funded by NIH and a philanthropic trust.

Hospice 52
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IV fluids in the ED: When do we really need them?

EMDocs

Sepsis There has been much controversy over the last two decades around the various nuances of volume resuscitation in ED patients with suspected sepsis, much of which goes beyond the scope of this limited review. 9 In terms of assessing volume status in general, Joseph et al. 11 A study by Stephan et al. Andrews et al. Inwald et al.