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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

At the time of discharge, thorough education and the availability of IM epinephrine for the patient is paramount to allow for prompt treatment of an unlikely biphasic reaction ( Pourmand 2018 , Shaker 2020 ). Incidence of clinically important biphasic reactions in emergency department patients with allergic reactions or anaphylaxis.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Second-generation H1 antihistamines (cetirizine, loratadine, and fexofenadine) do not cross the blood-brain barrier as easily (Bernstein J 2018). Patterson’s allergic diseases.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. 2018 Apr 17;319(15):1580-1591. Monami M, Marchionni N, Mannucci E.

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Grand Rounds Recap 3.15.23

Taming the SRU

Yates Anaphylaxis Pathophysiology Type 1 Hypersensitivity Reaction IgE-mediated Mast-cell degranulation of vasoactive materials Reaction occurs in minutes Clinical Definition: Acute onset of illness with involvement of the skin, mucosal tissue or both + one of the following Respiratory compromise Reduced BP Or, acute onset of illness with at least (..)

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

I’m Jeff Nusbaum, and I’m back with my co-host, Nachi Gupta and we’ll be taking you through the September 2018 issue of Emergency Medicine Practice - Emergency Department Management of North American Snake envenomations. Jeff: Welcome back to Emplify, the podcast corollary to EB Medicine’s Emergency Medicine Practice.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

However, in 2015 crotalidae equine immune F(ab’) 2 (ANAVIP®) was approved by the FDA for rattlesnake envenomations, and distribution of this antivenom began in 2018. Published online January 2018. 1,2 Discussion: F(ab) vs. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms. Crotalidae Immune F(ab’)2 (Equine). Accessed May 7, 2022.

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What the Emergency Clinician Must Know about Remote Monitors in Heart Failure

EMDocs

10 This procedure has well-described rare complications including infection, blood loss, allergic reaction, arrhythmia, pneumothorax if approaching via the internal jugular vein, embolization of the device, and pulmonary artery perforation or dissection. 2018 Jul;11(7):e004669. 8 The device itself is 2 x 2.5