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In 2021, an article was published (reference 1) that performed a systematic review of the literature from 2017 to 2020. Preventing death: This drug doesn’t appear to reduce mortality, which is the outcome we are most interested in when treating these patients. Thrombotic complications.
The disease is generally mild, but in untreated cases, it can lead to more severe outcomes, especially in patients with underlying conditions such as glucose-6-phosphate dehydrogenase deficiency. Even though the disease often resolves spontaneously, prompt antibiotic therapy is essential for optimal outcomes. 2017 Feb;166:16-24.
There was no difference in pain, return to work, functional outcome, or instrumentation failure. J Clin Neurosci 45:33-39, 2017. Listed in 2017, to be completed Nov 2026. It looked at loss of deformity correction, return to work, functional improvement, instrumentation failure rate, pseudoarthrosis, and postop complications.
Motor Fingernail bed pressure with a pencil first If flexion outcome, then apply painful stimulus to neck or head (trapezius or supraorbital notch) to look for localization Spinal reflex can result in a falsely elevated score if lower extremity pain induced Verbal Orientated- Able to answer all questions. A practical scale. PMID: 4136544.
It was published in European Heart Journal in 2017. Gorgels et al (5) looked at procainamide vs lidocaine and again and primary outcome was VTach termination. 2017 May 1;38(17):1329-1335. 2017 Apr;52(4):484-492. The most recent and well-known trial is the PROCAMIO trial (1). Great question. Eur Heart J. Long B, Koyfman A.
A 2008 Cochrane review found adult depression screening does not improve outcomes. The last two trials convincingly demonstrate that when patients with postpartum depression have better access to mental health services, outcomes improve. Screening had no impact on depression, anxiety, or a host of other mental health outcomes.
Interventions such as early application of hemorrhage control, tranexamic acid, reduction of crystalloid fluid administration and balanced ratio blood product transfusion have improved many patients’ outcomes. However, mortality still remains high due to trauma-induced coagulopathy. Severe acute traumatic coagulopathy = PT >1.5
What they did: Prospective randomized controlled trial, unblinded, multicenter study Conducted from January 2017 to December 2022 Patients with confirmed PSVT were randomly assigned to receive MVM, IV Adenosine, or combined therapy. The unblinded nature of the study could influence outcomes due to observer bias.
We aimed to determine the association between the 2020 COVID-19 pandemic and OHCA outcomes and bystander resuscitation efforts among the working-age population. We compared characteristics and outcome differences of the arrests between three prepandemic years (2017–2019) and the pandemic year 2020. to 1.20)).
Ann Emerg Med 2017 [6] This was a retrospective database review of 7521 traumatic brain injury patients SBP target ≥90mmHg resulted in a mortality of 7.8% vs SBP target <90mmHg which resulted in a mortality of 33.4% NEJM 1994. [2]
What They Did: Single-center, parallel, double blind, randomized controlled trial performed in a medical-surgical ICU (Mexico) Both groups received: Adjunctive vasopressin initiated at a dose of 0.03 NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4 NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4
This month's episode of EMplify, a podcast corollary to the Emergency Medicine Practice journal, focuses on management strategies that improve dental emergency outcomes. This podcast is based on the full-length review published in the June 2017 issue of Emergency Medicine Practice.
New York, Penguin Books; 2017. Ikigai and subsequent health and wellbeing among Japanese older adults: longitudinal outcome-wide analysis. The Experiment ; 2018. Garca H, Miralles F. Ikigai: The Japanese Secret to a Long and Happy Life. Okuzono S, Shiba K, Kim E, et al. Lancet Reg Health West Pac. 2022;21:100391.
Mortality is high, between 16-43.5% , and neurological outcomes are generally poor amongst survivors. These poor outcomes are related to both the SRSE itself and as a result of the prolonged PICU stay. One study suggests remission in 6 out of 7 patients where it was used, but long-term clinical outcomes remained poor.
Several secondary outcomes suggest a signal toward harm with hypothermia, including incidence of pneumonia, bradycardia, and more days ventilated. Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients with Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial. Bradycardia: 18.8%
mL/kg/hr for 2 consecutive hours OR Decrease in serum lactate by more than 10% from initial level Primary outcome – Early norepinephrine group vs. the control group demonstrated higher rates of shock control at 6 hours: 76.1% vs 48.4% (OR 3.4, vs 48.4% (OR 3.4, vs 48.4% (OR 3.4,
” I, then a 50-year-old associate professor of medicine, said those words over the phone to a friend late one night in 2017. By 2017, I had started to take a position that was uncomfortable for me, not because I didn’t believe it but because I knew it displeased others. . “I’m nervous. Why was I unsettled?
No difference in their primary outcome of complications and need for emergency surgery (1.9% 2017 Jan;104(1):52-61. Outcome measures were complicated diverticulitis, recurrent diverticulitis and sigmoid resection at 24 months’ follow up. Included 480 patients, with primary outcome return visit with hospital admission.
In studies including patients with trauma or Glasgow Coma Scale less than 8, intubation without sedation led to poorer neurological outcomes. The Impact of Prehospital Intubation with and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less. Journal of Neurosurgical Anesthesiology 29(2): p 161-167, April 2017. |
The last time we spoke in 2017, FemInEM was making waves by empowering women in emergency medicine and fostering conversations about gender equity. Can you elaborate on the evidence-based protocols and resources FemInEM plans to implement and how they will impact patient outcomes?
0000000000000305 Kazumi Y (2023) The Epidemiology and Outcomes of Leukopenia in Different Populations and Regions. An update on the diagnosis and treatment of chronic idiopathic neutropenia. Curr Opin Hematol. 2017;24(1):46-53. doi:10.1097/MOH.0000000000000305 J Blood Disord Transfus. 14:559 Tilahun, M., Gedefie, A., Ebrahim, E., Najivash, P.,
Outcome: No statistically significant difference in primary outcome, which was absence of clinically apparent seizures without the need for additional anti-convulsant medications AND improving responsiveness at 60 minutes after the start of trial-drug infusion, as determined by the treating physician.
Despite these findings, the World Health Organization (WHO), Infection Disease Society of America (IDSA) and the Center for Disease Control and Prevention (CDC) all continue to recommend use of oseltamivir, particularly in patients at increased risk of hospitalization and bad outcomes.
March 2023 * Population: Children 0-16 years recruited consecutively from October 2017 to September 2020 from three emergency departments and one urgent care centre in England- serving populations with significant inequalities in health and life expectancty. A prospective study. J Paediatr Child Health.
judgment vs. negligence” and “causation,” or the likelihood of a better outcome with earlier surgery). The case would last over several years, and with 85-90% of cases that go to trial resulting in a defense verdict, the outcome was unpredictable and risky. Updated: Oct 27, 2017. Medscape eMedicine.
More efficacious than parenteral opioids alone Safer than opioids Decreased delirium Patients have been shown to have improved functional outcomes at 30 days Early pain control matters! Currently EVT for large core is being looked at and so far the outcomes seem to be favorable
days 2 most common sites of infection were lung (44.8%) and inta-abdominal (32.1%) Majority of infections were community-acquired (≈84%) Over half the patients were on mechanical ventilation (≈53%) Primary Outcome Results: 28-day mortality rate: Placebo 26.1% (230/882) vs. XBJ 18.8% (165/878); P<0.001 The risk difference was 7.3% (95% CI, 3.4-11.2)
The podcast is based on the full-length review published in the May 2017 issue of Emergency Medicine Practice. The podcast is based on the full-length review published in the May 2017 issue of Emergency Medicine Practice.
Outcomes: Primary Outcome: Pulmonary expansion 24 hours after the procedure. Secondary Outcomes: Pulmonary expansion 7 days after the procedure. Blinding the outcome assessors to the initial assessment reduces the risk of measurement bias, enhancing the objectivity of the results.
In the CLEAR Outcomes trial, it was found effective in modestly reducing cholesterol and cardiovascular outcomes in statin-intolerant patients. The authors have now published a subanalysis of the main CLEAR Outcomes study. Bempedoic Acid is a cholesterol-lowering drug. Let’s first look at the original trial. placebo vs 11.7%
Wallace 2011 ) If addressed early and appropriately, most patients have good self-reported long-term outcomes regardless of the treatment modality Links Orthobullets: Achilles Tendon Rupture Resources: Sheth U et al. 2017; 99-B(1): 78-86. Bone Joint J. PMID: 28053261 Chiodo CP, Wilson MG.
This medication has limited outcomes data and multiple contraindications. On the other hand, naltrexone and acamprosate are well-tolerated, affordable medications with promising outcomes data for harm reductions and, in some cases, abstinence. Anton RF, O’Malley SS, Ciraulo DA, et al.
The lack of differences in the observed outcomes do not suggest one EM training length is superior. The additional year may improve career trajectory or longevity, entrance into fellowship or academic practice, or other longer-term outcomes including successful development of a niche in the specialty. 11 What should we take away?
And its correlation with outcomes varies. J Trauma Nursing 24(3):150-157, 2017. The most important one is that it relies only on the Injury Severity Score (ISS) to judge whether some type of mistriage occurred. The ISS is usually calculated after discharge, so it can only be applied after the fact. What is NFTI, Exactly?
2017-3068). 2017-0695) WBC count Absolute neutrophil count Procalcitonin (one model done without procal and one with) They repeated the same model for factors associated with IBI in febrile infants with UTIs. This definition of a positive UA and UTI were based on a prior PECARN study (doi.org/10.1542/peds.2017-3068).
HypoCa is common in trauma patients and is associated with poor outcomes. We need RCTs to determine if Ca administration in trauma impacts mortality and other patient-centered outcomes. All are associated with critical illness and severe hemorrhage. However, this triad does not include hypoCa, which has a major role in trauma.
As of 2017, just 15% of patients admitted to residential programs with opioid use disorder received any of the medications approved by the US Food and Drug Administration for treatment opioid use disorder – this despite the fact that those medicines save lives. These higher quality studies usually achieved better outcomes.
This is a critically important determination because of the 2017 AHA/ACC/HRS Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death.
[display_podcast] Date: September 2nd, 2017 Reference: Caputo et al. display_podcast] Date: September 2nd, 2017 Reference: Caputo et al. EmergeNcy Department use of Apneic Oxygenation versus usual care during rapid sequence intubation: A randomized controlled trial (The ENDAO Trial). Reference: Caputo et al.
2,3 In general, patients who develop cardiac arrest with an initial rhythm of VT or VF tend to have favorable outcomes compared to patients who develop cardiac arrest from either asystole or pulseless electrical activity. Heart disease and stroke statistics-2017 update: A report from the American Heart Association. Circulation.
This study aimed to analyse the advice provided in NHS 111 calls, the duration between the call and ED attendance, and the outcomes of such attendances made by children and young people (C&YP). This linked-data study examined NHS 111 calls and ED outcomes. This linked-data study examined NHS 111 calls and ED outcomes.
The outcomes from different resuscitative interventions in a haemorrhagic shock model in porcine model: From: Watts et al. EMJ 2017; 34: 860-900. Epidemiology and aetiology of TCA in England… Resuscitation; 110 (2017): 90-94. The heart of the matter: utility of ultrasound of cardiac activity during traumatic arrest.
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