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Diagnostics: Inflammatory Markers

Taming the SRU

A 2017 review in the American Journal of Emergency Medicine reiterates that no single inflammatory markers (including CRP, ESR, and PCT) can be used as a stand-alone test to confirm or exclude infection, but instead advocates for using the tests as adjunctive information for emergency physicians to shape their pre-test probability of infection [26].

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The Latest in Critical Care, 10/30/23 (Issue #18)

PulmCCM

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

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EM@3AM: ESBL-Producing Organisms and Their Management

EMDocs

4 The incidence of ESBL-E identified in bacterial cultures in the United States increased by 53% from 2012 to 2017. 8 Workup and Diagnosis Evaluation should be tailored to the patient presentation, but may include studies such as: CBC, CMP, UA, lactate (if concern for sepsis), Cultures (blood, urine, etc.)

EMS 73
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Are we on the right TRACT? 

Don't Forget the Bubbles

Exclusion criteria included children with known chronic diseases, exclusively breast-fed infants , or those who had already received an immediate transfusion at presentation to the hospital prior to recruitment. 3,950 children were recruited between September 2014 to May 2017. Were the study groups similar at the start of the trial?

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Antibiotics in the paediatric emergency department

Don't Forget the Bubbles

This is true in life-threatening conditions such as sepsis. However, when children do not have features of sepsis, oral antibiotics are equally effective. The take home is that although IV antibiotics are key in sepsis management, oral antibiotics are equally as effective as IV antibiotics for children without critical illness.

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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Antibiotics are effectively the only thing standing between these patients and overwhelming sepsis. Epub 2017 Nov 22. Improving the immediate management of neutropenic sepsis in the UK: Lessons from a national audit. 2017 Jun;69(6):755-764. Neutropenic Fever: Fever (one reading of 38.3C Support Care Cancer. Clarke, R.

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The 79th Bubble Wrap x Bristol Royal Hospital For Children

Don't Forget the Bubbles

This study retrospectively identified 1,414 children, presenting to 15 UK EDs (2016 -2017), who had been screened for malaria. Reviewed by: John Coveney Article 2: How do we define sepsis in children? International Consensus Criteria for Pediatric Sepsis and Septic Shock. Paediatr Int Child Health. 2024 Jan 11:1-7.