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Sickle Cell Disease Module

Don't Forget the Bubbles

SCD, therefore, is not only a mechanical disease but there are also many other cellular and plasma factors as well as endothelial interaction that generate chronic inflammation. Be careful if the patient has received a recent blood transfusion since it may be misinterpreted as sickle cell trait instead of sickle cell disease.

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Are we on the right TRACT? 

Don't Forget the Bubbles

Transfusion Decisions in Severe Anaemia Reducing child mortality remains high on the global health agenda. Let’s take the humble blood transfusion – used in emergency departments across the globe and playing a key role in critical care. However, there is a huge variation in transfusion practice globally.

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Diagnostics: Blood Transfusion Reactions

Taming the SRU

In the era of modern medicine, blood transfusions are commonplace, especially in the emergency department. Transfusion reactions are a spectrum of adverse events that can occur with the transfusion of whole blood or any of its components. One of the major risk factors is receiving a blood transfusion in the past.

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Trauma Resuscitation Updates

RebelEM

Ann Emerg Med 2017 [6] This was a retrospective database review of 7521 traumatic brain injury patients SBP target ≥90mmHg resulted in a mortality of 7.8% Ann Emerg Med 2017 [6] This was a retrospective database review of 7521 traumatic brain injury patients SBP target ≥90mmHg resulted in a mortality of 7.8% NEJM 1994. [2] Shock 2012.

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A Beginner’s Guide to Vasoactive Drug use in Children with Septic Shock

Don't Forget the Bubbles

And lastly, it’s actually quite hard to see how well the cardiovascular system is working, and this is one of its measurable features. This works well for a while, but eventually, the heart beats too fast to fill adequately. The amount of blood that comes from the heart with each contraction is the stroke volume (SV).

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TEG-Guided Resuscitation of Patients with Cirrhosis and Non-Variceal Bleeding

RebelEM

A meta-analysis of fifteen RCTs comparing blood product transfusion rates of cardiothoracic and surgery patients found significantly lower transfusion rates of FFP in TEG/ROTEM guided group compared to traditional tests, with no difference in survival rates (Fahrendorff 2017). Published 2017 Apr 13. 2017;25(1):39.

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Bilious Vomiting in the Neonate

Mind The Bleep

Sathe M, 2017) Age at onset: Often diagnosed antenatally, but if not presents within a few hours of birth Presentation : Abdominal distension, failure to pass meconium, bilious vomiting. Sathe M, 2017) Barium enema in a neonate demonstrating a diffuse microcolon secondary to meconium ileus. NG feeds if not feeding well.

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