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Sickle Cell Disease Module

Don't Forget the Bubbles

The Kilifi algorithm includes five clinical situations that are common sickle cell presentations – clinical jaundice, severe anaemia, bone and joint infections, and stroke. Newborn screening: sickle cell screening is donethrough heel-prick blood at five days of life. Would you consider this patient for blood transfusion?

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A Beginner’s Guide to Vasoactive Drug use in Children with Septic Shock

Don't Forget the Bubbles

The amount of blood that comes from the heart with each contraction is the stroke volume (SV). The stroke volume is the difference between how full it is at the start and how full it is after a contraction. The next element of stroke volume is the emptying. Published 2021 Apr 16. link] Roland D. Don’t Forget The Bubbles.

Shock 143
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Neonatal Hypotension

Don't Forget the Bubbles

Neonatal hypotension can result from inadequate cardiac output, low systemic vascular resistance, or a combination of both, which are influenced by: Cardiac Output: Neonates, particularly preterm ones, may have compromised cardiac output due to myocardial immaturity, leading to reduced stroke volume and heart rate. El-Khuffash, A.

Sepsis 59
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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

MI or stroke). Secondary outcomes were early head injury related death (within 24 hours after injury), all-cause and cause-specific mortality, disability, vascular occlusive events (MI, stroke, DVT, PE), seizures, complications, neurosurgery, days of ICU care, and adverse events within 28 days. in the TXA group and 9.9%

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Subarachnoid hemorrhage: ED presentation, evaluation, and management

EMDocs

National Institutes of Health Stroke Scale (NIHSS) is 13; vital signs include pulse 86 beats/minute (bpm), blood pressure 164/94 mmHg, and saturation of 98% on room air. 14 The American Stroke Association (ASA) and American Heart Association (AHA) recommend SBP <160 mmHg until definitive management of the bleed is completed.

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Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (MINT Trial)

RebelEM

PMID 37952133 Clinical Question: In patients with acute myocardial infarction and anemia, does a restrictive or liberal transfusion strategy affect the risk of death or recurrent myocardial infarction at 30 days? in liberal) received a blood transfusion (2.3 Third universal definition of myocardial infarction. Circulation.