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SGEM#188: Icatibant Bites the Dust – For ACE-I Induced Angioedema

The Skeptics' Guide to EM

[display_podcast] Date: September 12th, 2017 Reference: Sinert et al. J Allergy Clin Immunol Pract 2017. display_podcast] Date: September 12th, 2017 Reference: Sinert et al. J Allergy Clin Immunol Pract 2017. Though this disorder is routinely treated with medications for anaphylaxis (i.e. Reference: Sinert et al.

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52 in 52 – #36: Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

EMDocs

Outcome: No statistically significant difference in primary outcome, which was absence of clinically apparent seizures without the need for additional anti-convulsant medications AND improving responsiveness at 60 minutes after the start of trial-drug infusion, as determined by the treating physician.

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Vasopressor Nonresponse

Northwestern EM Blog

Anaphylaxis Anaphylaxis may present as hypotension alone. Thus, it may easily be confused with a different form of shock and treated with vasopressors such as norepinephrine and vasopressin, which are not first line for anaphylaxis. 2017; 45(9): 1443-1449. Urticaria should prompt consideration of anaphylaxis.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

antibiotics, NSAIDs) Acute urticaria with angioedema or anaphylaxis provided that urticaria was still present after initial treatment and alleviation of anaphylaxis symptoms. Exclusion: Presented with acute anaphylaxis, and their acute anaphylactic symptoms had not yet been treated. J Allergy Clin Immunol. PMID: 14767453.

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Being a BASICS Doctor

Mind The Bleep

BASICS responders have additional skills and can provide pre-hospital emergency care to patients delivering time-critical interventions to improve outcomes. What is a BASICS responder and who can do it? Doctors can volunteer as responders with BASICS Scotland if they have undertaken a Pre-Hospital Emergency Care Course (PHECC).

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Review of the ATHOS 3 trial

Northwestern EM Blog

The ATHOS-3 trial in 2017 explored the efficacy of angiotensin II as a vasopressor for severe vasodilatory shock. The study was designed as a phase III multicenter randomized placebo control trial taking place across 75 intensive care units in the United States from 2015 to 2017.

Shock 52
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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

4] We also know that severe TBI is commonly associated with the development of intracranial hemorrhage where the presence and volume of blood are associated with increased mortality and poor outcomes.[5] Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury. JAMA Neurol.