RebelEM

JANUARY 23, 2023

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. antibiotics, NSAIDs) Acute urticaria with angioedema or anaphylaxis provided that urticaria was still present after initial treatment and alleviation of anaphylaxis symptoms.

Allergic Reactions 52

Allergic Reactions Anaphylaxis Urgent Care Emergency Department 52

RebelEM

SEPTEMBER 13, 2023

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

Allergic Reactions 104

Allergic Reactions Airway Management Anaphylaxis Emergency Department 104

EB Medicine

SEPTEMBER 1, 2018

Both are at the University of Florida Jacksonville, and they reviewed a total of 120 articles from 2006-2017, in addition to reviews from both Cochrane and Dare. Note that antivenom will NOT reverse anaphylaxis on its own. Side effects to NACSA include dermal reaction as the most common -- and anaphylaxis as the most severe.

Emergency Department 40

Emergency Department Poisoning Anaphylaxis Allergic Reactions 40