Northwestern EM Blog

FEBRUARY 14, 2022

The ATHOS-3 trial in 2017 explored the efficacy of angiotensin II as a vasopressor for severe vasodilatory shock. Severe shock is defined as persistent hypotension requiring vasopressors to maintain a mean arterial pressure of 65mmHg and serum lactate <2 despite adequate volume resuscitation.

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Shock Resuscitation Fluid Resuscitation Sepsis 52

PHEM Cast

JULY 14, 2016

Elsevier Ltd; 2015 Apr 1;46(4):528–35. Value of a rigid collar: in need of more research and better devices. Journal of Emergencies, Trauma, and Shock. 2015 May;78(5):943–8. Oteir AO, Smith K, Stoelwinder JU, Middleton J, Jennings PA. Should suspected cervical spinal cord injury be immobilised?: A systematic review.

Fractures 52

Fractures Hospitals Shock Research 52

RebelEM

OCTOBER 31, 2022

However, researchers will often group outcomes of varying clinical importance. Burke 2015) Subgroup analysis can lead to “false positives due to multiple comparisons, false negatives due to inadequate power, and limited ability to inform individual treatment decisions because patients have multiple characteristics that vary simultaneously.”

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Sepsis Outcomes Research Shock 52

Taming the SRU

FEBRUARY 19, 2024

This has been the central question of many research projects with variable outcomes. A recent observational study was performed to pragmatically assess clinically meaningful differences in BP in a diverse critically ill cohort with shock. Damping Damping is essentially the shock absorbers in the pressurized system. Keville, M.

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Shock Resuscitation Ultrasounds Research 59

Don't Forget the Bubbles

JANUARY 10, 2024

The factorial design chosen by Dr Maitland and her research group means that several comparisons in transfusion practice could be carried out at the same time. What were the research questions? Does the study address a clearly focused research question? N Engl J Med. 2019;381(5):407-419. Was blinding achieved?

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Blood Transfusions Research Outcomes Hospitals 78

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

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Sepsis Shock Hospitals Infectious Diseases 52

Don't Forget the Bubbles

JULY 26, 2023

For anyone approaching a structured ABC would be a priority to establish whether shock was present or not. Typical features include: HR >220bpm Narrow complex regular tachycardia P waves difficult to identify In this case there is no shock present so we can proceed to the right branch of the ALSG guideline.

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EKG/ECG Hospitals Shock Documentation/Coding 98

Advanced Emergency Nursing from AENJ

FEBRUARY 29, 2016

Perhaps, not insignificantly, they were accustomed to receiving systematized government-supplied medical and trauma care, with "shock rooms" receiving an influx of victims, as contrasted to those later who opposed "socialized medicine." 1950s & 1960s Resuscitation Research. Committee on Shock. Farrington, J.

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Emergency Nursing EMS Resuscitation Military 40

Advanced Emergency Nursing from AENJ

JANUARY 26, 2015

Journal of Emergencies, Trauma and Shock, 3(1), 39. Geoff Jara-Almonte, MD and Hilary Fairbrother, MD // Editor: Alex Koyfman, MD Resuscitation of the Pregnant Trauma Patient – Pearls and Pitfalls www.emdocs.net 2/6/2015 Desjardins, G. Journal of clinical and diagnostic research: JCDR, 8(10), FC05. Capriola, M. Sherwani, R.,

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OB/GYN Ultrasounds Emergency Department Resuscitation 40

PEMBlog

JUNE 5, 2024

It was inspired by a hot-off-the-presses publication from the Pediatric Emergency Care Applied Research Network (PECARN) focused on clinical decision rules for cervical spine imaging in children. Leonard JR, Jaffe DM, Kuppermann N, Olsen CS, Leonard JC; Pediatric Emergency Care Applied Research Network (PECARN) Cervical Spine Study Group.

Fractures 52

Fractures Pediatrics Radiology Radiology 52

ACEP Now

APRIL 3, 2024

1,2 However, the European TTM1 trial in 2013 showed similar outcomes for those cooled to 33 degrees Celsius compared to 36 degrees Celsius, leading to a 2015 AHA class I recommendation of “cooling between 32 degrees Celsius-36 degrees Celsius.” degrees Celsius. 5,6 In 2021, the TTM2 trial was published. Dr. Abella is the William G.

Hyperthermia / Hypothermia 40

Hyperthermia / Hypothermia Resuscitation Outcomes Hospitals 40

Taming the SRU

MAY 3, 2023

During the admission, she completed a course of broad-spectrum antibiotics and as the underlying shock state improved, she was also weaned off all vasopressor support. For a complete discussion of cardiogenic shock and right ventricular failure, please see this other Air Care Series post on the subject.

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Wellness Hospitals Shock Outcomes 52

EB Medicine

AUGUST 1, 2018

Jeff: There are a shocking 22 million past-month users of marijuana in the US, followed by pain relievers at 3.8 Jeff: This DEA designation limits the ability to do research and obtain federal funding for such research. Synthetics were initially developed in the 1980s largely for research purposes. 2015;313(24):2456-2473.

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Seizures Hyperthermia / Hypothermia Administration Dehydration 40

Don't Forget the Bubbles

DECEMBER 11, 2023

Neglect Emotional Physical A subsequent study, ‘ The Philadelphia ACE Study ’, in 2015, identified that community factors were routinely neglected from research and so added in five community domains. This is shocking, but they discovered a staggering dose-response model when they compared these results with medical histories.

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Wellness Research Outcomes Shock 104

Don't Forget the Bubbles

APRIL 7, 2025

Pediatr Rev March 2015; 36 (3): 92103. Best Practice & Research Clinical Endocrinology & Metabolism, 32, pp. Replace remaining deficits and maintenance fluid requirements evenly over 24 hours using 0.9% sodium chloride with 5% glucose administered intravenously. References Auron M, Raissouni N; Adrenal Insufficiency.

Dehydration 72

Dehydration Pediatrics Administration Seizures 72

RebelEM

MAY 15, 2024

Volume 21, Issue 6, June 2015, Pages 583-590 Perron T, Emara M, Ahmed S. BMC Health Services Research. Neutropenic Fever: Fever (one reading of 38.3C Give appropriate fluids, vasopressors, and antibiotics. Factors influencing mortality in neutropenic patients with haematologic malignancies or solid tumours with bloodstream infection.

Infectious Diseases 101

Infectious Diseases Administration Sepsis Anaphylaxis 101

EMDocs

DECEMBER 16, 2023

Heat stroke can lead to end-organ dysfunction such as rhabdomyolysis, disseminated intravascular coagulation, cardiogenic shock, liver failure, and cerebral edema. Broad-spectrum antibiotics (A) for septic shock are not inappropriate given the hyperthermia, tachycardia, and hypotension. BMC research notes , 8 , 758. Izumida, S.,

Hyperthermia / Hypothermia 94

Hyperthermia / Hypothermia EMS Stroke Seizures 94

Pediatric Emergency Playbook

JANUARY 1, 2017

Intranasal (IN) medications offer the advantage of a fast onset for moderate-to-severe pain ( Graudins 2015 ), either as monotherapy or as a bridge to parenteral treatment (Table 4). Needleless lidocaine injectors may facilitate IV placement without obscuring the target vein ( Spanos 2008 , Lunoe 2015 ).

Pediatrics 40

Pediatrics Soft Tissue Injuries Burns Emergency Department 40

Downeast Emergency Medicine

OCTOBER 21, 2021

We chose this topic for Journal Club with the goals to raise awareness around these shocking statistics, discuss etiologies behind these high rates of suicide, and to normalize the discussion around physician mental health.

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Documentation/Coding Emergency Department Shock Research 52

Sensible Medicine

AUGUST 14, 2024

Researchers comb through the victims’ genomes for mutations in cardiorespiratory function and autonomic arousal systems. The failure-to-rouse model of SIDS hypothesizes that when CO2 levels rise in the baby’s breathing environment, she is unable to move her head to find clean air due to a genetic flaw. Dr. Paul N.

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CDC Sepsis Research Pediatrics 99

Don't Forget the Bubbles

FEBRUARY 24, 2025

The condition increases blood viscosity and pulmonary vascular resistance, leading to pulmonary hypertension, haemodynamic collapse, and, ultimately, death due to hypoxaemia and refractory shock. Between 2002 and 2015, 200 infants with pertussis were placed on ECMO, but only 56 survived, representing a survival rate of just 28%.

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Pediatrics Outcomes Blood Transfusions Sepsis 59

EMDocs

JANUARY 16, 2025

Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study. 2015 Sep 16;19(1):325. but PPV ranges from 25.1-39.5%

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Sepsis Pediatrics Shock Hospitals 95

EMDocs

JANUARY 20, 2025

Patients were enrolled in these trials if they had signs of shock, with mortality ranging from 18-29%. 13 While there is good data that early antibiotics for patients in septic shock reduce mortality 18-19 the role of early and aggressive volume resuscitation and its impacts on patient-centered outcomes remain unclear. Inwald et al.

Dehydration 75

Dehydration Fluid Resuscitation Sepsis Resuscitation 75

Don't Forget the Bubbles

OCTOBER 9, 2023

The research that does exist shows that doctors experience incivility regularly. It shocked me how big an effect this expert had on the teams, especially given the studied teams usually worked together and had an average of seven years of neonatal experience. Let’s look at Bradley et al. That was the end of the conversation.

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Seizures Incident Reporting Emergency Department Research 116