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Trauma Resuscitation Updates

RebelEM

I recently gave a talk on the initial management of trauma patients with hemorrhagic shock. Clinical Take Home Point: In patients with TBI and hypovolemic shock, target a SBP or MAP ≥90mmHg, but know this is based on limited evidence. vs SBP target <90mmHg which resulted in a mortality of 33.4% NEJM 1994. [2]

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Clinical Conundrum: Should We Always Treat Fever in Patients with Sepsis?

RebelEM

One side argues that fever places additional physiological stress on patients, who are already ill ( Young 2015 ). On the other hand, fever may serve as a protective role by enhancing immune cell function and inhibiting pathogen growth and spread ( Young 2015 ). NEJM 2015; 373(23): 2215-24. PMID: 26436473 Schortgen F et al.

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Publication Bias and Therapeutic Fashion

Sensible Medicine

CAST shocked the world of cardiology because suppression of rhythm disturbances after MI had been an accepted practice. I was shocked at how many people said that they read Sensible Medicine. Anti-arrhythmic drugs killed 1 patient for every 29 we treated. They did not expect this 9-fold higher death rate.

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REBEL Cast Ep123: Reduced-Dose Systemic Peripheral Alteplase in Massive PE?

RebelEM

in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 to 4.0mg/hr typically given in EKOS therapy (See Below).

Stroke 130
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Serial PoCUS for ED Patients with Acute Dyspnea: Is More Actually Better?

RebelEM

What They Did: Design: Randomized, controlled, blinded-outcome trial Sites: Three emergency departments in Denmark Duration: October 9, 2019 to May 26, 2021. Outcomes: Primary Outcome: Reduction of dyspnea measured on a verbal dyspnea scale (VDS) from 0 to 10 recorded at enrollment, then at 2, 4, and 5 hours after arrival.

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REBEL Core Cast 132.0 – Recent-Onset AFib

RebelEM

Ann Emerg Med 2015; 65(5): 532-9. PMID: 25701296 The SGEM: Shock Through the Heart (Ottawa Aggressive Atrial Fibrillation Protocol) ALiEM: Atrial Fibrillation Rate Control in the ED: Calcium Channel Blockers or Beta Blockers. Ann Emerg Med 2015; 65(5): 532-9. J Emerg Med 2015. Read More Atzema CL, Barrett TW.

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Don’t Forget About the IO in the Critically Ill Patient

RebelEM

In these situations, the American Heart Association (AHA) and the European Resuscitation Council (ERC) of 2015 recommend the intraosseous (IO) route after the peripheral route and before the central venous route ( 1). 2015 PMID: 25768683 8 Leidel BA. This can often lead to significant delays in proper resuscitation. Trauma 1996.