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Probiotics don’t improve outcomes in children with acute gastroenteritis

PEMBlog

The trial found that LGG did not significantly improve outcomes compared to placebo. We found that probiotics did not improve patient outcomes when compared to placebo. N Engl J Med 2018; 379:2015-2026. Why is this important for patients and caregivers ? N Engl J Med. 2018 Nov 22;379(21):2002-2014. doi: 10.1056/NEJMoa1802598.

Outcomes 105
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Outcomes of adult patients discharged at scene by emergency medical services

Emergency Medicine Journal

Background The outcomes of patients who call an ambulance but are discharged at scene reflect the safety and quality of emergency medical service (EMS) care. While previous studies have examined the outcomes of patients discharged at scene, none have specifically focused on paramedic-initiated discharge.

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Trauma Resuscitation Updates

RebelEM

vs 3U) but no difference in mortality (Study not powered for this outcome) Clinical Take Home Point: The use of vasopressors is controversial and requires a nuanced approach SUMMARY OF MINIMIZING IATROGENIC INJURY RESTORE PERFUSION VOLUME REPLACEMENT Blood Products >>> Crystalloids Holcomb JB et al. NEJM 1994. [2]

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The Modified Valsalva Maneuver: Practical Treatment or Pointless Trick?

RebelEM

Background: The REVERT Randomized Controlled Trial demonstrated the superiority of the modified valsalva maneuver (MVM) over the standard valsalva maneuver (VM) in re-establishing normal sinus rhythm (NSR) in patients with PSVT (Appelboam 2015). The unblinded nature of the study could influence outcomes due to observer bias.

Outcomes 132
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The UK-REBOA trial

First 10 EM

There have been some observational studies that suggested REBOA was associated with worse outcomes, but the outcomes were largely assumed to be the result of confounders. Norii 2015, […] The post The UK-REBOA trial appeared first on First10EM.

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Optimising the post-crash response – Russell Gruen TAC-MUARC Symposium 2015

ETM Course

If you’re interested in trauma systems and their effect on patient outcomes, this is a great presentation by Russell Gruen at the recent TAC – MUARC Symposium.

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Does squeezing an arm really hard improve outcomes after cardiac surgery?

PulmCCM

This is a remarkable example of the differences between societies, which might influence the processes of clinical trials and their outcomes. RIPC has not been shown to improve cardiovascular outcomes more generally after cardiac surgery. Circulation. 2024 Sep 25. doi: 10.1161/CIRCULATIONAHA.124.071408. 124.071408. Epub ahead of print.