Remove 2015 Remove Allergic Reactions Remove Anaphylaxis
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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis? Bottom Line Up Top: After prompt recognition and appropriate treatment with IM epinephrine, the risk of biphasic reactions are exceedingly low. mg of intramuscular (IM) epinephrine for anaphylaxis. This is called a biphasic reaction.

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Grand Rounds Recap 3.15.23

Taming the SRU

massive bee envenomation - R4 Capstone - Hydrocephalus - cpc: brain tumor - hyperviscosity syndromes - the language of being well & embracing fear in emergency medicine tamingthesru: Massive bee envenomation WITH dr. Yates Anaphylaxis Pathophysiology Type 1 Hypersensitivity Reaction IgE-mediated Mast-cell degranulation of vasoactive materials Reaction (..)

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REBEL Core Cast 108.0 – Angioedema

RebelEM

Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

As some background, from 2006-2015 there were almost 66,000 reported snake exposures and 31 deaths from snake envenomation in the US. Jeff: Hypotension should be treated with isotonic fluids and, as usual, anaphylaxis should be treated with the usual cocktail of antihistamines and epinephrine at first IM and then via infusion if refractory.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

However, in 2015 crotalidae equine immune F(ab’) 2 (ANAVIP®) was approved by the FDA for rattlesnake envenomations, and distribution of this antivenom began in 2018. 1,2 Discussion: F(ab) vs. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.