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Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

RebelEM

How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis? mg of intramuscular (IM) epinephrine for anaphylaxis. What The Evidence Says: Prompt recognition of anaphylaxis is imperative. up to 23% ( Lieberman 2005 , Rohacek 2014 , Tole 2007 , Grunau 2014 ). His vital signs are normal.

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Anaphylaxis and angioedema have been reported, primarily with exendin-based therapies such as exenatide and lixisenatide. 2014 Fall-Winter;11(3-4):202-30. FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014. Reactions are usually minor: transient warmth, pruritis at injection site that resolves.

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Annals of B Pod: Anti-Xa Overdose

Taming the SRU

The patient is agitated on a backboard with C-collar in place. Laboratory assessment of the anticoagulant activity of direct oral anticoagulants: a systematic review. Jan; 151(1): 127-138. Cuker A, et al. Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants. J Am Coll Cardiol. Sep 16; 64(11): 1128-39.

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Review of the ATHOS 3 trial

Northwestern EM Blog

Source control timely antibiotics, rational fluid resuscitation, and ruling out other causes of vasopressor refractory shock to include anaphylaxis, hemorrhage, adrenal insufficiency, LVOT obstruction, and any other cause of cardiogenic shock need to be ruled out and addressed. Crit Care 2014; 18(5): 534. References Chawla LS et al.

Shock 52
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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

2014 Aug 21;124(8):1251-8; quiz 1378. doi: 10.1182/blood-2014-02-482612. Epub 2014 May 28. 2014, November 10). 2014 Jul; 58(7): 3799–3803. Neutropenic Fever: Fever (one reading of 38.3C Raad, II, et al., Gibson C, Berliner N. How we evaluate and treat neutropenia in adults. Gorschlüter M, Mey U, Strehl J, et al.

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emDOCs Podcast – Episode 91: Marine Envenomation and Trauma

EMDocs

Philadelphia: Elsevier Saunders; 2014:805-807. Venomous Marine Animals. In: Marx JA, Hockenberger RS, Biros MH, et al., Rosen’s Emergency Medicine: Concepts and Clinical Practice (2 Volumes). Dustin Taliaferro, Dustin, Cynthia Santos, MD, Alex Koyfman, MD, and Brit Long. 2020, September 26) EM@3AM: Marine Animal Bites and Stings.

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Severe Asthma Management in the ED

EM Guide Wire

mcg/kg/min Can increase dose q30 min to max dose of 10 mcg/kg/min Can cause elevations in troponin If there hasn’t been improving, consider IM epinephrine instead Same as anaphylaxis dose 0.01 mg inhaled over the first hour of therapy Followed by 0.5 mg may be nebulized Q4-6 hours. 2015 Oct-Dec; 27(4): 390–396.