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Anti-NMDA Receptor Encephalitis in Children and Adolescents

Pediatric EM Morsels

Higher titers in both CSF and serum were associated with poor outcomes. Treat the seizures , but…. Keep in mind that seizure management can be difficult and the patient may not respond to AEDs. Earlier diagnosis leads to better outcomes. It is best to assume the worst and cover for this possibility. doi: 10.1212/NXI.0000000000200013.

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emDOCs Revamp: Alcohol Withdrawal

EMDocs

2013; 88(9): 589-595. fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold Alcohol withdrawal syndrome in medical patients. Cleve Clin J Med. 2016; 83(1): 67-79.

Seizures 105
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Congenital Syphilis

Pediatric EM Morsels

Foles, 2024 ] In the US, from 2013-2018, cases increased from 362 to 1,306. If not treated early, then increased risk of poor outcomes and death. 2013 Aug;20(4):337-9. Epub 2013 Feb 27. Worldwide, congenital syphilis complicates about 1 million pregnancies / year. Rates of congenital syphilis are increasing. BMJ Case Rep.

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The Current Status of Continuous-Seizure Management

ACEP Now

35-year-old man presents by EMS with seizures. According to family at the scene, he has a history of seizures but has not been taking his medication recently. On arrival, he is obtunded, foaming at the mouth, and exhibiting generalized tonic-clonic seizure activity. Clinical Question » How should status epilepticus be diagnosed?

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TXA in head injuries

Don't Forget the Bubbles

CRASH 2 , published in 2013 – was huge. The primary outcome was 28-day mortality – TXA improved survival with no increased risk of cerebral clots. Even if they excluded patients with a GCS of 3 or unreactive pupils at enrollment, outcomes were not better in the TXA group ( 12.5% This is not good.

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SGEM#239: Febrile Seizure Recurrence – With or Without You Acetaminophen?

The Skeptics' Guide to EM

Acetaminophen and febrile seizure recurrences during the same fever episode. He specialises in Paediatric Emergency Medicine and is a passionate […] The post SGEM#239: Febrile Seizure Recurrence – With or Without You Acetaminophen? Acetaminophen and febrile seizure recurrences during the same fever episode. Pediatrics.

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52 in 52 – #41: The CENSER Trial

EMDocs

mL/kg/hr for 2 consecutive hours OR Decrease in serum lactate by more than 10% from initial level Primary outcome – Early norepinephrine group vs. the control group demonstrated higher rates of shock control at 6 hours: 76.1% vs 48.4% (OR 3.4, vs 48.4% (OR 3.4, vs 48.4% (OR 3.4, vs 48.4% (OR 3.4,

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