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Congenital Syphilis

Pediatric EM Morsels

We have previously discussed hypothermia presentations , GBS infections , and HSV infections. Foles, 2024 ] In the US, from 2013-2018, cases increased from 362 to 1,306. 2013 Aug;20(4):337-9. Epub 2013 Feb 27. Fortunately, we have addressed many neonatal issues in the PedEMMorsels. BMJ Case Rep. 2021 Feb 5;14(2):e240532.

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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM

With severe toxicity, patients can have altered mental status, seizures, hyperthermia, and pulmonary edema. 2013 May;5(5):330. Salicylate has a direct effect on the respiratory center of the medulla causing tachypnea. Tinnitus, nausea, vomiting, and abdominal pain are common. Phytotherapy Research. 2015;29(8):1112-1116. PMID: 25997859.

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The Latest in Critical Care, 1/22/24 (Issue #26)

PulmCCM

Background Therapeutic hypothermia, later rebranded as targeted temperature management, became a standard post-cardiac arrest therapy for comatose patients after two 2002 NEJM trials ( n=273 and n=77 ) suggested reducing core temperature to 32°C to 34°C markedly improved neurologic outcomes and survival. Read on for details.

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emDOCs Revamp: Alcohol Withdrawal

EMDocs

2013; 88(9): 589-595. fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold fold higher risk of NSTI than the control group 12 For those without comorbidities , AUD exhibited a 15.2-fold Alcohol withdrawal syndrome in medical patients. Cleve Clin J Med. 2016; 83(1): 67-79.

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SGEM#336: You Can’t Always Get What You Want – TTM2 Trial

The Skeptics' Guide to EM

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest. Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest. Background: Hypothermia has been a mainstay of post-arrest care after the publication of two trials in 2002 that both suggested a benefit. This gives a NNT of 4.

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The Science on Targeted Temperature Management

ACEP Now

Early work on TTM in 2002 showed benefit to cooling to 33 degrees Celsius, which subsequently influenced international resuscitation guidelines to recommend mild hypothermia at 32 degrees to 34 degrees Celsius in 2005. Adding nuance, this study also showed that the highest-severity arrests did not benefit from hypothermia.

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Targeted temperature management for post-cardiac arrest is officially over (for now)

PulmCCM

Background Therapeutic hypothermia, later rebranded as targeted temperature management, became a standard post-cardiac arrest therapy for comatose patients after two 2002 NEJM trials ( n=273 and n=77 ) suggested reducing core temperature to 32°C to 34°C markedly improved neurologic outcomes and survival. Read on for details.