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TXA in head injuries

Don't Forget the Bubbles

No, I don’t give TXA to kids with isolated head injuries We want to stop any clot breakdown to try and slow any potential bleeding. CRASH 2 , published in 2013 – was huge. What about head injury , though? Along came the CRASH 3 trial, another huge study looking specifically at TXA in traumatic brain injury.

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Episode 30: Head injury

PHEM Cast

[link] Quite a few of our previous podcasts include content which is relevant to this Head Injury one. Autoregulation Allows giraffes to drink from pools without a rush of blood to the head and eat leaves from trees without fainting. Doubts over head injury studies. Mannitol for acute traumatic brain injury.

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SGEM#412: I Can’t Choose…from all the Head Injury Prediction Rules

The Skeptics' Guide to EM

Comparison of PECARN, CATCH, and CHALICE rules for children with minor head injury: a prospective cohort study. He is a […] The post SGEM#412: I Can’t Choose…from all the Head Injury Prediction Rules first appeared on The Skeptics Guide to Emergency Medicine. So, should we CT scan children with minor head injury?

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Unwrapping PEM excellence at IAEM23

Don't Forget the Bubbles

The primary survey confirms isolated head injury – Bee’s drowsy, and a formal GCS is 12 – E3, V4, M5. You’ve two options: Yes – give TXA No – don’t give TXA The 2013 CRASH 2 international multicentre RCT compared TXA with placebo in >20,000 adult trauma patients. But what about the evidence of TXA in isolated head injury?

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emDOCs Podcast – Episode 81: Hemophilia

EMDocs

A 2013 study found oral mucosal and head bleeding due to injury were most common in those < 6 months. PECARN Pediatric Head Injury/Trauma Algorithm, Canadian CT Head Injury Rule, Ottawa Knee and Ankle Rules) do not apply to those with hemophilia and should not guide management. PMID: 19637999.

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Episode 16: “Blood”

PHEM Cast

Early correction of hypotension (especially if blunt trauma / associated head injury) The balances of harms in the context of blunt trauma between the negative effects of infusing saline versus the negative effects of hypotension are unknown and prehospital actions need to be customised to an individual patient and situation.

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Annals of B Pod: Anti-Xa Overdose

Taming the SRU

After rescue, she had an apparent head injury and was confused but protecting her airway with grossly normal vital signs. She initially agreed to be transported to the hospital by ambulance, but jumped from the moving vehicle and was subsequently struck and pinned under the fuselage for 10-15 minutes. Blood Coagul Fibrinolysis.