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ToxCard: Iron

EMDocs

Blood transfusion for clinically significant blood loss. 5 Consider exchange transfusion in addition to deferoxamine for serum iron concentrations greater than 1000 g/dL, or those who clinically deteriorate despite supportive care and chelation. Published 2012 Jul 1. 2012 Aug;39(8):719-24. PMID: 15939855.

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Trauma Resuscitation Updates

RebelEM

Lancet 2010 [10] >20,000 adult trauma patients with SBP <90mmHg Patients randomized to TXA 1g over 10 min + 1g IV over 8hrs vs Placebo given within 8hrs of injury In-hospital mortality by 28d reduced (14.5% NEJM 1994. [2]

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

Massive Blood Transfusion Following Older Adult Trauma: the Effect of Blood Ratios on Mortality. AEM December 2022 Guest Skeptic: Dr. Kirsty Challen is a Consultant in Emergency Medicine at Lancashire Teaching Hospitals. Massive Blood Transfusion Following Older Adult Trauma: the Effect of Blood Ratios on Mortality.

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Episode 16: “Blood”

PHEM Cast

Penn-Barwell JG, Roberts SA, Midwinter MJ, Bishop JR: Improved survival in UK combat casualties from Iraq and Afghanistan: 2003-2012. Prehospital transfusion of plasma and red blood cells in trauma patients. .: Prehospital transfusion of plasma and red blood cells in trauma patients. J Trauma Acute Care Surg.

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SGEM#210: (Don’t) Let it Bleed – TXA for Epistaxis in Patients on Anti-Platelet Drugs

The Skeptics' Guide to EM

Guest Skeptic: Dr. Justin Morgenstern is an emergency physician and the Director of Simulation Education at Markham Stouffville Hospital in Ontario. Guest Skeptic: Dr. Justin Morgenstern is an emergency physician and the Director of Simulation Education at Markham Stouffville Hospital in Ontario. AEM March 2018. AEM March 2018.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

Four level-1 US trauma centers participated in the study where the inclusion criteria were trauma patients who were within 2 hours of their injury and were transported to the trauma center from either the field or another hospital. The primary outcome was head injury-related death in-hospital within 28 days of injury.

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Subarachnoid hemorrhage: ED presentation, evaluation, and management

EMDocs

10,11 Magnetic resonance imaging (MRI) is not recommended as a primary imaging modality for the diagnosis of SAH due to test duration (which can delay life-saving interventions), as well as the fact that the mixing of blood with cerebrospinal fluid (CSF) may delay the transition of hemoglobin to its deoxyhemoglobin state that is best imaged on MRI.