RebelEM

MAY 25, 2023

Severe Traumatic Brain Injury and Controlled Hemorrhage in Rats: Quest for the Optimal Mean Arterial Blood Pressure After Whole Fresh Donor Blood Resuscitation. Shock 2012. Association of out-of- hospital hypotension depth and duration with traumatic brain injury mortality. PMID: 31461138 Brotfain E et al.

Resuscitation 145

Resuscitation Fluid Resuscitation Head Injuries Shock 145

PHEM Cast

FEBRUARY 23, 2017

Early correction of hypotension (especially if blunt trauma / associated head injury) The balances of harms in the context of blunt trauma between the negative effects of infusing saline versus the negative effects of hypotension are unknown and prehospital actions need to be customised to an individual patient and situation.

Blood Transfusions 52

Blood Transfusions Head Injuries Resuscitation Radiology 52

Downeast Emergency Medicine

APRIL 26, 2021

CRASH-3 TRIAL COLLABORATORS This international, multi-center, randomized, placebo-controlled trial looked at the effects of TXA on head injury-related death, disability, and adverse events in adult patients with TBI. The primary outcome was head injury-related death in-hospital within 28 days of injury.

Head Injuries 52

Head Injuries Administration Outcomes Seizures 52