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REBEL Core Cast 108.0 – Angioedema

RebelEM

These chemicals can recruit other cells, like eosinophils, and may lead to anaphylaxis. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.

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SGEM #427: I Want a Treatment with a Short Course…for Pediatric Urinary Tract Infections

The Skeptics' Guide to EM

The American Academy of Pediatrics ( AAP ) released guidelines for the management of febrile infants and children 2 to 24 months back in 2011 [2]. UTIs are one of the most common bacterial infections in childhood that we see in the emergency department [1].

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emDOCs Podcast – Episode 94: GLP-1 Agonist Complications

EMDocs

Anaphylaxis and angioedema have been reported, primarily with exendin-based therapies such as exenatide and lixisenatide. 2011 Aug 02;108(3 Suppl):33B-41B. 2011;(203):53-74. Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction.

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Annals of B Pod: Anti-Xa Overdose

Taming the SRU

DISCUSSION Epidemiology and Background Rivaroxaban, along with other direct oral anticoagulants (DOACs), has become a mainstay of treatment for pro-thrombotic conditions since 2011. [1] The patient is agitated on a backboard with C-collar in place. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. Samana, MM.

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Approach to Shock

Pediatric Emergency Playbook

If so, treat the cause – perhaps this is a distributive problem due to anaphylaxis. 2011; Apr 26;123(16):1788-830. 2011; 39:450. After assessing the heart rate, optimizing volume status, evaluating contractility, is the cause of the shock peripheral vasodilation? Treat with epinephrine. Circulation. Levy B et al. Crit Care Med.

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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

2011 Jun;153(6):773-9. Epub 2011 Apr 22 Coyne CJ, Le V, Brennan JJ, Castillo EM, Shatsky RA, Ferran K, Brodine S, Vilke GM. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america, Clinical Infectious Diseases, 2011, 52(4):e56-93.

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Grand Rounds Recap 8.16.23

Taming the SRU

for detecting major injuries Abnormal CXR Rapid deceleration mechanism Presence of a distracting injury Chest wall tenderness Sternal/thoracic spine/scapular tenderness There are limited decision-making rules for thoracic spine imaging Yet a study (Inaba et al., 2015) reported a sensitivity of 98.9%

Sepsis 95