2011 Allergic Reactions Anaphylaxis 
RebelEM
SEPTEMBER 13, 2023
Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. Features Urticaria and pruritis Rapid onset (1-2 hours) IgE Dependent (Type I Hypersensitivity) Reactions An allergen cross-links two or more IgE molecules on mast cells or basophils and initiates a signal cascade leading to degranulation.
EMDocs
FEBRUARY 7, 2024
Hypersensitivity/dermatologic: GLP-1 agonists are synthetic peptides; may lead to antibody formation and allergic reaction/injection site reaction. Reactions are usually minor: transient warmth, pruritis at injection site that resolves. 2011 Aug 02;108(3 Suppl):33B-41B. 2011;(203):53-74. Diabetes Metab.
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