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ToxCard: Diethylene Glycol

EMDocs

In mass poisoning cases, DEG has been substituted as a solvent in oral medications and in topical medicinal products. DGA concentrates in the kidney tissue and causes nephrotoxicity, as well as neurotoxicity. Elimination half-life data is not well established but increases in larger overdoses and as renal injury begins to occur.

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ToxCard: Bupropion

EMDocs

3 Bupropion blocks the reuptake of dopamine and norepinephrine, as well as antagonizes acetylcholine at nicotinic receptors. 6,15 Discuss cases of overdose, including pediatric exploratory ingestions, with a medical toxicologist or your local poison center. 2010; 48(8):800-5 Robinson S. Accessed 12/18/2022. Clin Toxicol (Phila).

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Annals of B Pod: Social EM Corner- Suicide Related Behaviors

Taming the SRU

In conjunction with the Drug and Poison Information Center (DPIC), intravenous methylene blue was initiated for suspected methemoglobinemia with moderate improvement of her symptoms over the next hour, including return of baseline mental status and resolution of hypoxia. Published 2010. Psychol Med. 2006;36(2):145-157.

EMS 97
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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

Nachi: And don’t forget our peer reviewers this month, Dr. Daniel Sessions, a medical toxicologist working at the South Texas Poison Center, and our very own editor-in-chief, Dr. Andy Jagoda, who is also Chair of the Department of Emergency Medicine at Mount Sinai in New York City. Jeff: What a team! But, let’s get back to the snakes.

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Carbon Dioxide As A Resuscitative Gas

Advanced Emergency Nursing from AENJ

Even after no longer having a role in resuscitation, CO2 was advocated for accelerating clearance of carbon monoxide poisoning into the 1950s and 1960s. Henderson , it would seem, was an enthusiast, well-convinced of his opinions, with missionary zeal, who would firmly argue his positions and tirelessly campaign them. In 1927, H.W.

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Episode 19 - Cannabinoids: Emerging Evidence in Use and Abuse

EB Medicine

Jeff: Because the current DEA controlled substances schedule designations are based on original chemical names, synthetics have gained popularity as manufacturers are able to produce newer compounds and circumvent DEA designation as well as routine urine drug screening tests. Jeff: And the etiology of CHS is not well understood.

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Is Splenic Dysfunction Correlated with Sickle Cell Anemia in Kids?

ACEP Now

A multi-institutional, randomized, double-blinded, placebo-controlled trial (the BABY HUG trial) evaluated spleen size as well as serum labs and splenic dye uptake of technetium-labeled sulfur colloid. Bloodstream infections in children with sickle cell disease: 2010-2019. References Cober MP, Phelps SJ. J Pediatr Pharmacol Ther.