RebelEM

MAY 25, 2023

vs 3U) but no difference in mortality (Study not powered for this outcome) Clinical Take Home Point: The use of vasopressors is controversial and requires a nuanced approach SUMMARY OF MINIMIZING IATROGENIC INJURY RESTORE PERFUSION VOLUME REPLACEMENT Blood Products >>> Crystalloids Holcomb JB et al. NEJM 1994. [2]

Resuscitation 145

Resuscitation Fluid Resuscitation Head Injuries Shock 145

RebelEM

JUNE 19, 2023

PMID: 37314244 Clinical Question: In advanced trauma systems, does prehospital administration of TXA increase the rate of survival with a favorable neurologic outcome in patients at risk for trauma-induced coagulopathy? 1.00 (0.9 – 1.12) Secondary Outcome Mortality 24h 9.7% Prehospital Tranexamic Acid for Severe Trauma.

Blood Transfusions 105

Blood Transfusions Outcomes Administration Hyperthermia / Hypothermia 105

RebelEM

JANUARY 24, 2024

Wallace 2011 ) If addressed early and appropriately, most patients have good self-reported long-term outcomes regardless of the treatment modality Links Orthobullets: Achilles Tendon Rupture Resources: Sheth U et al. 2010; 92(17): 2767-75. PMID: 22538958 Willits K et al. Bone Joint Surg Am. PMID: 21037028 Wallace RG et al.

Operations 101

Operations Ultrasounds Fractures Outcomes 101

RebelEM

JANUARY 29, 2024

in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 in the paper but 2.7% to ≈0.99 (p<0.001) Mean MPI/Tei Index≈ 0.47 to 4.0mg/hr typically given in EKOS therapy (See Below). to 4.0mg/hr typically given in EKOS therapy (See Below).

Stroke 136

Stroke Outcomes Hospitals Administration 136

EMDocs

JUNE 1, 2023

Several secondary outcomes suggest a signal toward harm with hypothermia, including incidence of pneumonia, bradycardia, and more days ventilated. Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients with Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial. Bradycardia: 18.8%

Hyperthermia / Hypothermia 87

Hyperthermia / Hypothermia Outcomes Hospitals Emergency Department 87

EMDocs

JANUARY 25, 2025

0000000000000305 Kazumi Y (2023) The Epidemiology and Outcomes of Leukopenia in Different Populations and Regions. Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Curr Opin Hematol. 2017;24(1):46-53. doi:10.1097/MOH.0000000000000305

EMS 96

EMS Infectious Diseases Allergic Reactions Fluid Resuscitation 96

EMDocs

JUNE 8, 2023

and 9 hours after onset of symptoms, with non-infarcted brain tissue, does the administration of alteplase improve functional outcome at 90 days? and 9 hours of symptom onset; stroke symptoms that started during sleep were assumed to have started halfway between the actual last known well and the time of wake-up. Intervention: Alteplase 0.9

Stroke 98

Stroke Administration Documentation/Coding Outcomes 98

PulmCCM

MAY 12, 2024

Unfortunately, neurologic outcomes have remained poor over that time, with most survivors of out-of-hospital cardiac arrest remaining severely disabled. At least as far back as 2010, ghrelin was found to enhance dopaminergic neuronal survival , and is under stud… Read more

Hospitals 59

Hospitals Outcomes 59

Don't Forget the Bubbles

AUGUST 2, 2023

Early management leads to better outcomes. That being said, younger patients tend to have better outcomes with a multidisciplinary team approach leading to remission in approximately 90% of children. Outcomes of children with complex regional pain syndrome after intensive inpatient rehabilitation. Pain Res Manag. 2015;351:h2730.

Psychiatric 98

Psychiatric Pediatrics Outcomes Fractures 98

The Skeptics' Guide to EM

MAY 30, 2020

The evidence for TXA providing a patient-oriented outcome (POO) has been mixed. It seems to work for epistaxis ( SGEM#53 and SGEM#210 ), failed to demonstrate a decrease in all-cause mortality in post-partum hemorrhage ( SGEM#214 ), and did not result in an improved neurologic outcome in hemorrhagic strokes ( SGEM#236 ). TXA vs. 19.8%

Head Injuries 52

Head Injuries Academics EMS Stroke 52

Sensible Medicine

APRIL 16, 2024

The tool developed on the PLCO participants was used to analyze the CXRs of outpatients taken in 2010 or 2011 at 1 of 2 hospitals ( The General or The Brigham ). The primary outcome was incident MACE within 10 years of the CXR in populations who either did or did not have data from which ASCVD could be calculated.

Radiology 96

Radiology Radiology Stroke Hospitals 96

Don't Forget the Bubbles

MAY 6, 2024

This multicentre retrospective cohort study looked at 202 children in California aged 1- 24 months who presented acutely between 2010 and 2021. Outcomes included clinical status when urine culture was available, subsequent antibiotic treatment within seven days and subsequent UTI within 30 days. Why does it matter?

Sepsis 75

Sepsis Pediatrics Outcomes Documentation/Coding 75

PulmCCM

JANUARY 22, 2024

Background Therapeutic hypothermia, later rebranded as targeted temperature management, became a standard post-cardiac arrest therapy for comatose patients after two 2002 NEJM trials ( n=273 and n=77 ) suggested reducing core temperature to 32°C to 34°C markedly improved neurologic outcomes and survival.

Hyperthermia / Hypothermia 80

Hyperthermia / Hypothermia Outcomes Research Hospitals 80

Dr. Smith's ECG Blog

JUNE 27, 2024

A reliable study would keep track of all patients with shockable arrest and analyze the ones who were not enrolled to see their outcomes. A patient like this one would not be enrolled because no clinician (ER doc or cardiologist) would enroll such a patient. This study failed to do so. 5% vs. 58%!!

Resuscitation 113

Resuscitation EKG/ECG Outcomes Hospitals 113

PHEM Cast

JULY 27, 2021

Intensive Care Med 2010; 36: 1475-83. Kenji Inaba. 2015 Marik PE, Cavallazzi R. Does central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Cavallaro F, Sandroni C, Marano C, et al.

Ultrasounds 52

Ultrasounds Fractures Resuscitation EMS 52

The Skeptics' Guide to EM

JUNE 11, 2017

Taking antiplatelet therapy prior to a hemorrhagic stroke raises the risk of death by 27% and in high income countries more than 25% of patients with incident intracerebral hemorrhages were taking antiplatelet therapy (Thompson et al Neurology 2010). However, recommendations from the neurosurgical perspective differ.

Stroke 52

Stroke EMS Outcomes 52

The Skeptics' Guide to EM

FEBRUARY 26, 2019

Dr. Hoffman has published a graphic re-analysis of NINDS ( Annals EM 2009 ) and Sayer et al responded in print ( Annals EM 2010 ). The SGEM did a Classic Episode on NINDS with Anand Swaminathan ( SGEM#70 ). The other major trial that we discussed was the IST-3 study which was covered on SGEM#29.

Stroke 52

Stroke EMS Research Outcomes 52

Pediatric Emergency Playbook

OCTOBER 1, 2017

2010; 30:76–81. Outcomes of Children Bridged to Heart Transplantation With Ventricular Assist Devices: A Multi-Institutional Study. 2010; 6: 46-53. Journal of Chemical Neuroanatomy; 2011; 42: 288–296. Intrathecal Pumps Borowski A, Littleton AG, Borkhuu B et al. J Pediatr Orthop. Ghosh D, Mainali G, Khera J, Luciano M.

Pediatrics 52

Pediatrics Seizures Stroke Ultrasounds 52

SheMD

MAY 11, 2023

In medical emergencies, provider qualities which lead to greater performance and patient outcomes include leadership and teamwork. What were their outcomes: Of the 182 teams analyzed, females contributed significantly less leadership statements (53% vs 76%, p=0.001) and critical treatment decisions (57% vs 76%, p=0.018). Crit Care Med.

Leadership 52

Leadership Documentation/Coding CPR Teamwork 52

The Skeptics' Guide to EM

OCTOBER 17, 2020

Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury. Background: The CRASH-2 trial, published in 2010, showed a 1.5% Reference: Rowell et al. Other injuries appear minimal with some abrasions from the fall. Reference: Rowell et al.

EMS 52

EMS Head Injuries Outcomes Hospitals 52

All Ohio EM

SEPTEMBER 16, 2019

By Mike Pallaci, DO Research Question: Does rapid lowering of blood pressure improve the outcome in patients with intracerebral hemorrhage? The primary outcome was determined for 2794 of these; 45 patients (1.6%) lost to follow-up. How Many Patients: The investigators enrolled 2839 patients.

Stroke 40

Stroke Outcomes Research Hospitals 40

PHEM Cast

APRIL 10, 2016

This was the same principle as in the Rivers trial: the standard care group is the ‘control’ group against which changes in outcome for the ‘intervention’ group are compared. 2010 Apr;38(4):1045–53. EMS Patients and Walk-In Patients Presenting With Severe Sepsis: Differences in Management and Outcome. 2010 Apr;14(2):145–52.

Sepsis 52

Sepsis Fluid Resuscitation Resuscitation Emergency Department 52

Pediatric Emergency Playbook

AUGUST 1, 2017

2010; 26:769-781. 2010; 149(3):386-391. Does Functional Outcome Improve with Time Postsurgery for Hirschsprung Disease? Single-stage versus multi-stage pull-through for Hirschsprung's disease: practice trends and outcomes in infants. 2010; 45:1182-1186. 2010; 28(11):544-548. 2010 Oct;40(4):613-20. .

Pediatrics 52

Pediatrics Ultrasounds Resuscitation Sepsis 52

Broome Docs

APRIL 6, 2023

Renal outcomes following intravenous contrast administration in patients with acute kidney injury: a multi-site retrospective propensity-adjusted analysis. 2010 Oct 5;182(14):1527-32. Epub 2010 Aug 23. Clinical Outcomes After Intensifying Antihypertensive Medication Regimens Among Older Adults at Hospital Discharge.

Sepsis 52

Sepsis Ultrasounds Hospitals Fractures 52

Taming the SRU

OCTOBER 1, 2023

As these patients are typically already at a high risk for poor health outcomes, secondary spontaneous PTX is often more serious in presentation and management more complex [11]. Management of spontaneous pneumothorax: British Thoracic Society Pleural Disease Guideline 2010. J Emerg Med. 2021;61(5):517-528. doi:10.1016/j.jemermed.2021.07.006

Fractures 96

Fractures COPD Hospitals Emergency Department 96

American Medical Compliance

APRIL 17, 2024

Our Continuing Medical Education (CME) program is committed to enhancing the knowledge, skills, and professional performance of healthcare providers to improve healthcare outcomes. American Medical Compliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing education to physicians.

Outcomes 52

Outcomes 52

EMDocs

SEPTEMBER 7, 2023

1, 2010, pp. Long-Term Renal and Neurologic Outcomes among Survivors of Diethylene Glycol Poisoning.” “Inhibition of Metabolism of Diethylene Glycol Prevents Target Organ Toxicity in Rats.” Toxicological Sciences , vol. link] Ballentine, Carol. Sulfanilamide Disaster.” FDA Consumer Magazine , June 1981, [link] Accessed August 2022.

Poisoning 94

Poisoning CDC Administration Emergency Department 94

ACEP Now

MAY 10, 2024

Primary Outcome: Diagnostic accuracy of identifying Stanford type A and Stanford type B AoDs Secondary Outcomes: Test characteristics of each of the three individual sonographic findings for diagnosing Stanford type A and Stanford type B AoDs. Acad Emerg Med. 2024;31(2):112-118. Eur Heart J. 2014;35:2873-2926. J Am Coll Cardiol.

Ultrasounds 52

Ultrasounds Outcomes Academics Documentation/Coding 52

RebelEM

SEPTEMBER 26, 2022

Randomized study design Blind adjudication of transfusion reaction outcomes Follow-up was complete. The primary outcome was disease-oriented The enrolled cohort appears to be a convenience sample Sealed envelopes are a weak type of allocation and prone to error and manipulation. Significant coagulopathy: INR > 1.8

Resuscitation 52

Resuscitation Blood Transfusions Outcomes Hospitals 52

RebelEM

JANUARY 25, 2023

2010, (Ch) 92: p 1216-1227. Small bowel obstruction: Outcome and cost implications of admitting service. Am Surg 2010; 76:687-691. 2.3 – 5.4) (-) LR: 0.18 (0.09 – 0.35) Ultrasound Findings Dilated loops of bowel (diameter > 2.5 3.6 – 55.6) (-) LR: 0.13 (0.08 – 0.20) ED US (+) LR: 9.5 (2.1

Operations 52

Operations Sepsis Resuscitation Ultrasounds 52

RebelEM

JANUARY 23, 2023

Despite being highly effective in treating acute allergic reactions, first-generation H1 antihistamines cross the blood-brain barrier and bind to H1 receptors, which can lead to undesirable side effects, including drowsiness, sedation, fatigue, and decreased cognition (Church MK 2010). 2010 Apr;65(4):459-66. Epub 2010 Feb 8.

Allergic Reactions 52

Allergic Reactions Anaphylaxis Emergency Department Urgent Care 52

ACEP Now

SEPTEMBER 3, 2024

Private equity investment in health care has increased more than 20-fold since 2000, with 70 percent of this activity since 2010. Evaluating trends in private equity ownership and impacts on health outcomes, costs and quality: systematic review. Borsa A, Bejarano G, Ellen M, et al. 2023;382:e075244. Kannan S, Bruch JD, Song Z.

Hospitals 113

Hospitals Radiology Radiology Emergency Department 113

EMDocs

JANUARY 4, 2024

Whole bowel irrigation: 3 Not routinely performed and limited evidence to support improved outcome in general. 2010; 48(8):800-5 Robinson S. Clinical characteristics and outcomes associated with bupropion overdose: a Canadian perspective. Can consider in massive overdose, especially of SR or XL formulations. Am J Emerg Med.

Seizures 94

Seizures EKG/ECG Poisoning Shock 94

Dr. Smith's ECG Blog

OCTOBER 20, 2013

We studied this and published the abstract below in 2010. Chicago November 2010. Data collected included demographics, initial rhythm, EKG, emergency department (ED) CT and outcomes. The data was analyzed in relation to initial rhythm, outcomes and changes or delay in treatment. Circulation 122:Abstract 101.

Resuscitation 52

Resuscitation EKG/ECG Hospitals Emergency Department 52

American Medical Compliance

JULY 9, 2024

Our Continuing Medical Education (CME) program is committed to enhancing the knowledge, skills, and professional performance of healthcare providers to improve patient care outcomes. By understanding these different types, healthcare providers can better protect and support vulnerable elders.

Elder Abuse 52

Elder Abuse Documentation/Coding Outcomes Wellness 52

RebelEM

MARCH 13, 2023

Nevertheless, mortality of prehospital traumatic cardiac arrest (TCA), and survivability with good neurologic outcome, remain the gold standards of trauma care in and out of the hospital and are effectively the criterion by which we measure outcomes in the trauma literature. Discussion: Dead On Scene: The 96.2% mortality rate and 43.5%

Basic Life Support 52

Basic Life Support EMS Outcomes Resuscitation 52

The Skeptics' Guide to EM

FEBRUARY 25, 2023

The latest guidelines from the AHA in 2020 state, “clinical trials and observational studies since the 2010 guidelines have yielded no new evidence that routine administration of sodium bicarbonate improves outcomes from undifferentiated cardiac arrest and evidence suggests that it may worsen survival and neurological recovery.” [4]

Pediatrics 52

Pediatrics Hospitals CPR Resuscitation 52