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EM@3AM: Murine Typhus

EMDocs

Clinical Infectious Diseases , vol. Ischemic Hepatitis and Septic Shock Secondary to Murine Typhus Infection in Pregnancy. State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus. 2010 Feb;28(1):29-56, vii.

EMS 105
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Clinical Conundrums: Should You Give the First Dose of Antibiotics IV Before Discharging Home on Oral Antibiotics?

RebelEM

Except for patients with poor gut absorption or those with critical infectious processes such as septic shock or necrotizing fasciitis, this belief appears to be unfounded. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Eur Resp J 2010; 35: 858-64.

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Diagnostics: Inflammatory Markers

Taming the SRU

Spinal Infection: According to the Infectious Disease Society of America’s (IDSA) 2015 guidelines for native vertebral osteomyelitis, CRP and ESR in the setting of protracted back pain have sensitivities ranging from 94 to 100% for ruling out infection and malignancy in these patients. N Engl J Med. 2023 Feb 2;388(5):439-452.

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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Read More: Infectious Disease Society of America 2010 Clinical Practice Guidelines Life in the Fast Lane: Febrile Neutropaenia Uptodate: overview of neutropenic fever syndromes EMRAP: Risk stratification of neutropenic fever MDCalc: MASCC Score MDCalc: CISNE Score References: Ahn S, Rice TW, Yeung SJ, Cooksley T. Mullen, C.

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Episode 24 - First Trimester Pregnancy Emergencies: Recognition and Management

EB Medicine

A 2010 Meta-Analysis found a NPV of 99.96% when an er doc identified an IUP on bedside ultrasound. Per a 2010 and 2011 Cochrane review, there is not evidence to recommend one antibiotic over another, so let your local antibiograms guide your treatment. So keep doing your bedside scans with confidence.

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Going beyond the surface material: A podcast episode on cellulitis

PEMBlog

Camargo, Clinical Trial: Comparative Effectiveness of Cephalexin Plus Trimethoprim-Sulfamethoxazole Versus Cephalexin Alone for Treatment of Uncomplicated Cellulitis: A Randomized Controlled Trial, Clinical Infectious Diseases, Volume 56, Issue 12, 15 June 2013, Pages 1754–1762, [link] Liu C, Bayer A, Cosgrove SE, et al. Pediatrics.

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Leucodepletion in Bordetella Pertussis

Don't Forget the Bubbles

The condition increases blood viscosity and pulmonary vascular resistance, leading to pulmonary hypertension, haemodynamic collapse, and, ultimately, death due to hypoxaemia and refractory shock. The Pediatric Infectious Disease Journal 37(3):p 202-205, March 2018. This involved routing a leucocyte filter into the ECMO circuit.