SGEM#293: CRASH in the US, CRASH in the US, CRASH-2 in the USA
The Skeptics' Guide to EM
MAY 30, 2020
It seems to work for epistaxis ( SGEM#53 and SGEM#210 ), failed to demonstrate a decrease in all-cause mortality in post-partum hemorrhage ( SGEM#214 ), and did not result in an improved neurologic outcome in hemorrhagic strokes ( SGEM#236 ). This study published in 2010 showed an absolute mortality reduction of 1.5% TXA vs. 19.8%
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