Remove 2010 Remove Blood Transfusions Remove Seizures
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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1] Lancet 2010; 376:23-32.[

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TXA (Tranexamic Acid) in PediatricsĀ 

Pediatric EM Morsels

While transfusing blood can be beneficial to those who have lost it or continue to lose it quickly, blood may not always be immediately available. Or maybe the family does not desire blood transfusions. Enter TXA or tranexamic acid , The Clot Stabilizer! of IV form TXA [O’Neill 2020] Inexpensive !

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Sickle Cell Disease Module

Don't Forget the Bubbles

Be careful if the patient has received a recent blood transfusion since it may be misinterpreted as sickle cell trait instead of sickle cell disease. In these cases, repeat the Hb electrophoresis three months after the last blood transfusion. Do not use pethidine since it can cause seizures and CNS hyperexcitability.

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Leucodepletion in Bordetella Pertussis

Don't Forget the Bubbles

Infants usually present in a non-specific manner, following an apnoea, cough, cyanosis, or seizure so a high index of suspicion is required in this age group. Exchange blood transfusion in the management of severe pertussis in young infants. Exchange transfusion safety and outcomes in neonatal hyperbilirubinemia.